Protein Alignment Set and SETSIP

DIOPT Version :9

• Sequence 1: NP_650438.2
• Gene: Set / 41844
• FlyBaseID: FBgn0014879
• Length: 269
• Species: Drosophila melanogaster
• Sequence 2: NP_001274666.1
• Gene: SETSIP / 646817
• HGNCID: 42937
• Length: 302
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 163/292 - (55%)
• Similarity: 206/292 - (70%)
• Gaps: 38/292 - (13%)

  Fly     2 SSVPKR--------AKLDGAPADG--NTSAAAG----NNEEESEALEQIDACQNEIDALNEKASE 52
            |..|||        .|....||.|  .|||:||    ..:|:.||:|.||..|||||.|||:.||
Human    10 SMAPKRQSPLPLQKKKPRPPPALGLEETSASAGLPKKGEKEQQEAIEHIDEVQNEIDRLNEQDSE 74

  Fly    53 EILKVEQKYNKLRKPCYEKRSELVKRIPNFWVTSFINHPQVSGILDEEEEECLHALNKLEVEEFE 117
            |||||||||||||:|.::|||||:.:||||.||:|:||||||.:|.||:||.||.|.|:||.|||
Human    75 EILKVEQKYNKLRQPFFQKRSELIAKIPNFGVTTFVNHPQVSSLLGEEDEEALHYLTKVEVTEFE 139

  Fly   118 DIKSGYRINFHFDENPYFENKVLTKEFHLNSAAASENGDWPASTSTPIKWKEGKNLLK-LLLTKP 181
            ||||||||:|:|||||||||||.:||||||     |:|| |:|.||.||||.||::.| ...|:.
Human   140 DIKSGYRIDFYFDENPYFENKVFSKEFHLN-----ESGD-PSSKSTKIKWKSGKDVTKRSSQTQN 198

  Fly   182 YGNKKKRNSEYKTFFDWFSDNTDPVNDEIAELIKDDLWPNPLQYYLVPDIEVEPEDEEDNEDNDE 246
            ..::|:::.|.::||.||:|::|...||:.|:||||:||||||||||||:    :|||..||:|:
Human   199 KASRKRQHEEPESFFTWFTDHSDAGADELEEVIKDDIWPNPLQYYLVPDM----DDEEGGEDDDD 259

  Fly   247 EAFDDEDGEDGEGE----------EEEEDEDD 268
               ||:||::||.|          |.||||||
Human   260 ---DDDDGDEGEEELEDIDEGDEDEGEEDEDD 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Set	NP_650438.2	NAP	31..227	CDD:279323	124/196 (63%)
SETSIP	NP_001274666.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53		14/42 (33%)
		NAP	60..244	CDD:279323	119/189 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	168..302		64/134 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151998
Domainoid	1	1.000	197	1.000	Domainoid score	I3099
eggNOG	1	0.900	-	-		E1_KOG1508
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2596
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55441
OrthoDB	1	1.010	-	-		D518537at33208
OrthoFinder	1	1.000	-	-		FOG0000644
OrthoInspector	1	1.000	-	-		otm42145
orthoMCL	1	0.900	-	-		OOG6_103113
Panther	1	1.100	-	-	LDO	PTHR11875
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2181
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	13	12.810