DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Set and gmip

DIOPT Version :9

Sequence 1:	NP_650438.2	Gene:	Set / 41844	FlyBaseID:	FBgn0014879	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	XP_031753686.1	Gene:	gmip / 448355	XenbaseID:	XB-GENE-977540	Length:	950	Species:	Xenopus tropicalis

Alignment Length:	199	Identity:	40/199 - (20%)
Similarity:	71/199 - (35%)	Gaps:	61/199 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KRAKLDGAP------ADGNTSAAAGNNEEESEALEQIDACQNEIDALNEKASEEILKVEQKYNKL 64
            ::|||..|.      |.|:|.:|....|:..::.|:..:...|.:|......:|.....|:..|:
Frog   297 EKAKLLSAKIEEEQIASGHTGSANKLVEKRRKSREEAQSKAIEAEASYRSCVQEANARSQQQEKV 361

  Fly    65 RKPCYEKRSELVKRIPNFWVTSFINHPQVSGILDEEEEECLHALNKLEVEEFEDIKSGYRINFHF 129
            |:.                :.|.|....:.|  |:..:|....|.:::..:||.|..||
Frog   362 RER----------------IVSHIRKLIIQG--DQVLKEVTMNLLRMKQSQFEAIPCGY------ 402

  Fly   130 DENPYFENKVLTKEFHLNSAAASENGDWPASTSTPIKWKEGKNLLKLLLTKPYGNKKKRNSEYKT 194
                                     ||. .:|..|  ::.|...|:.:||.|   :|..:.|..|
Frog   403 -------------------------GDL-LTTCDP--YESGTRYLQFILTLP---RKHTDPEKFT 436

  Fly   195 FFDW 198
            |.::
Frog   437 FEEY 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Set	NP_650438.2	NAP	31..227	CDD:279323	31/168 (18%)
gmip	XP_031753686.1	BAR	156..380	CDD:416402	20/100 (20%)
		C1_GMIP-like	575..624	CDD:410366
		RhoGAP_GMIP	632..827	CDD:239873
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1508
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.860