DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Set and TSPYL6

DIOPT Version :9

Sequence 1:	NP_650438.2	Gene:	Set / 41844	FlyBaseID:	FBgn0014879	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_001003937.2	Gene:	TSPYL6 / 388951	HGNCID:	14521	Length:	410	Species:	Homo sapiens

Alignment Length:	246	Identity:	75/246 - (30%)
Similarity:	128/246 - (52%)	Gaps:	36/246 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PKRAKLDGAPADGNTSAAAGNNEEESEALEQI----------------------DACQNEIDALN 47
            |:...:..||.|........:..||:.|::::                      ::.|.|:|::|
Human   152 PEECAMFSAPVDEKPGGEEMDVAEENRAIDEVNREAGPGPGPGPLNVGLHLNPLESIQLELDSVN 216

  Fly    48 EKASEEILKVEQKYNKLRKPCYEKRSELVKRIPNFWVTSFINHPQVSGILDEEEEECLHALNKLE 112
            .:|...:|:||:::.::.:...|:|:::::.||.||||:|.:|||:|.::..::.|.|..|..||
Human   217 AEADRALLQVERRFGQIHEYYLEQRNDIIRNIPGFWVTAFRHHPQLSAMIRGQDAEMLSYLTNLE 281

  Fly   113 VEEFEDIKSGYRINFHFDENPYFENKVLTKEFHLNSAAASENGDWPASTSTPIKWKEGKNLLKLL 177
            |:|....::|.:..|.|..||||.||::.|.:.:.|...      ..|.||.|.|:.|..
Human   282 VKELRHPRTGCKFKFFFQRNPYFRNKLIVKVYEVRSFGQ------VVSFSTLIMWRRGHG----- 335

  Fly   178 LTKPYGNKKKRNSEYKTFFDWFSDNTDPVNDEIAELIKDDLWPNPLQYYLV 228
               |.....:......:||.||||::.|.:|.||::||:|||.|||||||:
Human   336 ---PQSFIHRNRHVICSFFTWFSDHSLPESDRIAQIIKEDLWSNPLQYYLL 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Set	NP_650438.2	NAP	31..227	CDD:279323	67/217 (31%)
TSPYL6	NP_001003937.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	46..69
		NAP	205..382	CDD:298680	66/190 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152058
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1508
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1191764at2759
OrthoFinder	1	1.000	-	-		FOG0000644
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11875
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.810