DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Set and seta

DIOPT Version :9

Sequence 1:	NP_650438.2	Gene:	Set / 41844	FlyBaseID:	FBgn0014879	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_958883.1	Gene:	seta / 323501	ZFINID:	ZDB-GENE-030131-2221	Length:	269	Species:	Danio rerio

Alignment Length:	245	Identity:	151/245 - (61%)
Similarity:	192/245 - (78%)	Gaps:	9/245 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 NNEEESEALEQIDACQNEIDALNEKASEEILKVEQKYNKLRKPCYEKRSELVKRIPNFWVTSFIN 89
            :.:|:.||:|.||..|||||.|||:||||||||||||||||:|.::|||||:.:|||||||:|:|
Zfish    24 SEKEQQEAIEHIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVN 88

  Fly    90 HPQVSGILDEEEEECLHALNKLEVEEFEDIKSGYRINFHFDENPYFENKVLTKEFHLNSAAASEN 154
            |||||.:|.||:||.||.|.::||.|||||||||||:|:||||.|||||||:||.|||     |:
Zfish    89 HPQVSALLGEEDEEALHYLTRVEVTEFEDIKSGYRIDFYFDENMYFENKVLSKEIHLN-----ES 148

  Fly   155 GDWPASTSTPIKWKEGKNLL-KLLLTKPYGNKKKRNSEYKTFFDWFSDNTDPVNDEIAELIKDDL 218
            || |.|.||.||||.||:|. :...|:....||:::.|.::||.||:|:.|...||:.|:||||:
Zfish   149 GD-PTSKSTEIKWKPGKDLTSRSSQTQSKAGKKRQHEEPESFFTWFTDHADSGADELGEVIKDDI 212

  Fly   219 WPNPLQYYLVPDIEVEPEDEEDNEDNDEEAFDDEDGEDGEGEEEEEDEDD 268
            ||||||||||||:|.| |.|.::||:|||..||.| |:|:.:.||||:||
Zfish   213 WPNPLQYYLVPDMEDE-EGEGEDEDDDEEGLDDID-EEGDDDGEEEDDDD 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Set	NP_650438.2	NAP	31..227	CDD:279323	125/196 (64%)
seta	NP_958883.1	NAP	37..221	CDD:279323	120/189 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	196	1.000	Domainoid score	I3078
eggNOG	1	0.900	-	-		E1_KOG1508
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	304	1.000	Inparanoid score	I2633
OMA	1	1.010	-	-		QHG55441
OrthoDB	1	1.010	-	-		D1191764at2759
OrthoFinder	1	1.000	-	-		FOG0000644
OrthoInspector	1	1.000	-	-		otm24515
orthoMCL	1	0.900	-	-		OOG6_103113
Panther	1	1.100	-	-	O	PTHR11875
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R11118
SonicParanoid	1	1.000	-	-		X2181
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910