DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Set and setb

DIOPT Version :9

Sequence 1:	NP_650438.2	Gene:	Set / 41844	FlyBaseID:	FBgn0014879	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_958876.1	Gene:	setb / 321714	ZFINID:	ZDB-GENE-030131-433	Length:	275	Species:	Danio rerio

Alignment Length:	272	Identity:	157/272 - (57%)
Similarity:	204/272 - (75%)	Gaps:	17/272 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 AKLDGAPADGNTSAAAGNNE-EESEALEQIDACQNEIDALNEKASEEILKVEQKYNKLRKPCYEK 71
            ||:.....:.|...|...:| |:.||:|.||..|||||.|||:||||||||||||||||:|.::|
Zfish     6 AKVSRKEQNSNHDGADETSEKEQQEAIEHIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFQK 70

  Fly    72 RSELVKRIPNFWVTSFINHPQVSGILDEEEEECLHALNKLEVEEFEDIKSGYRINFHFDENPYFE 136
            ||||:.:|||||||:|:||||||.:|.||:||.||.|.::||.|||||||||||:|:||||||||
Zfish    71 RSELIAKIPNFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTEFEDIKSGYRIDFYFDENPYFE 135

  Fly   137 NKVLTKEFHLNSAAASENGDWPASTSTPIKWKEGKNLLKLLLTKP-YGNKKKRNSEYKTFFDWFS 200
            ||||:||||||     |:|| |:|.||.||||.||:|.|.....| ...||:::.|.::||.||:
Zfish   136 NKVLSKEFHLN-----ESGD-PSSKSTEIKWKAGKDLTKRTGQTPNKAGKKRQHEEPESFFTWFT 194

  Fly   201 DNTDPVNDEIAELIKDDLWPNPLQYYLVPDI-EVEPEDEEDNEDNDEEAFD--DEDGEDGEGEEE 262
            |::|...||:.|:||||:||||||||||||: |.|.|.||::::.:||..:  ||:|::.:|||:
Zfish   195 DHSDAGADELGEVIKDDIWPNPLQYYLVPDMDEEEGEGEEEDDEEEEEGLEDIDEEGDEDDGEED 259

  Fly   263 EED------EDD 268
            ||:      |||
Zfish   260 EEEDEGEDGEDD 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Set	NP_650438.2	NAP	31..227	CDD:279323	128/196 (65%)
setb	NP_958876.1	NAP	37..221	CDD:279323	123/189 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	196	1.000	Domainoid score	I3078
eggNOG	1	0.900	-	-		E1_KOG1508
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55707
Inparanoid	1	1.050	304	1.000	Inparanoid score	I2633
OMA	1	1.010	-	-		QHG55441
OrthoDB	1	1.010	-	-		D1191764at2759
OrthoFinder	1	1.000	-	-		FOG0000644
OrthoInspector	1	1.000	-	-		otm24515
orthoMCL	1	0.900	-	-		OOG6_103113
Panther	1	1.100	-	-	LDO	PTHR11875
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2181
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.880