DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Set and Set

DIOPT Version :9

Sequence 1:	NP_650438.2	Gene:	Set / 41844	FlyBaseID:	FBgn0014879	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_001012522.1	Gene:	Set / 307947	RGDID:	1307467	Length:	289	Species:	Rattus norvegicus

Alignment Length:	283	Identity:	159/283 - (56%)
Similarity:	208/283 - (73%)	Gaps:	25/283 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PKRAKLDGAPADGNTSAAAG---NNEEESEALEQIDACQNEIDALNEKASEEILKVEQKYNKLRK 66
            ||:.:...||...:.||:.|   ..:|:.||:|.||..|||||.|||:||||||||||||||||:
  Rat    13 PKKPRPVAAPKLEDKSASPGLPKGEKEQQEAIEHIDEVQNEIDRLNEQASEEILKVEQKYNKLRQ 77

  Fly    67 PCYEKRSELVKRIPNFWVTSFINHPQVSGILDEEEEECLHALNKLEVEEFEDIKSGYRINFHFDE 131
            |.::|||||:.:|||||||:|:||||||.:|.||:||.||.|.::||.|||||||||||:|:|||
  Rat    78 PFFQKRSELITKIPNFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTEFEDIKSGYRIDFYFDE 142

  Fly   132 NPYFENKVLTKEFHLNSAAASENGDWPASTSTPIKWKEGKNLLKL-LLTKPYGNKKKRNSEYKTF 195
            |||||||||:||||||     |:|| |:|.||.||||.||:|.|. ..|:...::|:::.|.::|
  Rat   143 NPYFENKVLSKEFHLN-----ESGD-PSSKSTEIKWKSGKDLTKCSSQTQNKASRKRQHEEPESF 201

  Fly   196 FDWFSDNTDPVNDEIAELIKDDLWPNPLQYYLVPDIEVEPEDEEDNEDNDEEAFD----DEDGED 256
            |.||:|::|...||:.|:||||:||||||||||||::.|..:.||::|:|||...    ||:|::
  Rat   202 FTWFTDHSDAGADELGEVIKDDIWPNPLQYYLVPDMDDEEGEAEDDDDDDEEEEGLEDIDEEGDE 266

  Fly   257 GEGE-----------EEEEDEDD 268
            .|||           ||:|.|||
  Rat   267 DEGEEDNDEDEGEEGEEDEGEDD 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Set	NP_650438.2	NAP	31..227	CDD:279323	127/196 (65%)
Set	NP_001012522.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42		10/31 (32%)
		Dimerization. /evidence=ECO:0000250	31..77		32/48 (67%)
		NAP	49..233	CDD:279323	119/184 (65%)
		Earmuff domain. /evidence=ECO:0000250	78..224		87/146 (60%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	157..206		20/49 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	235..289		23/57 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345522
Domainoid	1	1.000	197	1.000	Domainoid score	I3009
eggNOG	1	0.900	-	-		E1_KOG1508
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55707
Inparanoid	1	1.050	309	1.000	Inparanoid score	I2531
OMA	1	1.010	-	-		QHG55441
OrthoDB	1	1.010	-	-		D1191764at2759
OrthoFinder	1	1.000	-	-		FOG0000644
OrthoInspector	1	1.000	-	-		otm46292
orthoMCL	1	0.900	-	-		OOG6_103113
Panther	1	1.100	-	-	LDO	PTHR11875
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2181
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810