DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Set and Tspyl5

DIOPT Version :9

Sequence 1:	NP_650438.2	Gene:	Set / 41844	FlyBaseID:	FBgn0014879	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_001078890.1	Gene:	Tspyl5 / 239364	MGIID:	2442458	Length:	406	Species:	Mus musculus

Alignment Length:	257	Identity:	89/257 - (34%)
Similarity:	138/257 - (53%)	Gaps:	41/257 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RAKLDGAP--ADGNTSAAAGNNEEES--------------EALEQIDACQNEIDALNEKASEEIL 55
            :|.:.|.|  |.....|||...||:.              .:::.::..|.:::.:|.:|....|
Mouse   154 QATVSGKPKMASAGLCAAAPVGEEKKMTEKHAGAGSPATVGSMDTLETVQLKLETMNAQADRAYL 218

  Fly    56 KVEQKYNKLRKPCYEKRSELVKRIPNFWVTSFINHPQVSGILDEEEEECLHALNKLEVEEFEDIK 120
            ::.:|:.:||....|:|:.|::.||.||..:|.||||:|..|:.:::|.|..||:|||||....:
Mouse   219 RLSRKFGQLRLHHLERRNLLIQSIPGFWGQAFQNHPQLSAFLNTKDKEVLSYLNRLEVEELGLAR 283

  Fly   121 SGYRINFHFDENPYFENKVLTKEFHLNSAAASENGDWPA----STSTPIKWKEGKNLLKLLLTKP 181
            .||:|.|:|..||||:||||.||:          |..|:    |.|.||:|..|.:|..|....|
Mouse   284 LGYKIKFYFGRNPYFQNKVLIKEY----------GCGPSGQVVSRSAPIQWLPGHDLQSLSKENP 338

  Fly   182 YGNKKKRNSEYKTFFDWFSDNTDPVNDEIAELIKDDLWPNPLQYYLVPDIEVEPEDEEDNED 243
            ..|        .:||.|||:::...:|:|.|:|.:|||||||||||:.:   |...|:..|:
Mouse   339 ENN--------GSFFGWFSNHSSIESDKIVEIINEDLWPNPLQYYLISE---EARGEKGKEE 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Set	NP_650438.2	NAP	31..227	CDD:279323	75/199 (38%)
Tspyl5	NP_001078890.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..67
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	132..164		3/9 (33%)
		NAP	217..367	CDD:298680	63/167 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	382..406		2/8 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842138
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1508
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1191764at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11875
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.810