DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Set and TSPYL4

DIOPT Version :9

Sequence 1:NP_650438.2 Gene:Set / 41844 FlyBaseID:FBgn0014879 Length:269 Species:Drosophila melanogaster
Sequence 2:NP_067680.3 Gene:TSPYL4 / 23270 HGNCID:21559 Length:414 Species:Homo sapiens


Alignment Length:244 Identity:80/244 - (32%)
Similarity:133/244 - (54%) Gaps:33/244 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 KRAKLDGAPADGNTSAA-------------AGNNEEE--------SEALEQIDACQNEIDALNEK 49
            |||.......:|...||             ||..:||        :..::.::|...|:..:|.:
Human   156 KRAISAAVEKEGEAGAAMEEKKVVQKEKKVAGGVKEETRPRAPKINNCMDSLEAIDQELSNVNAQ 220

  Fly    50 ASEEILKVEQKYNKLRKPCYEKRSELVKRIPNFWVTSFINHPQVSGILDEEEEECLHALNKLEVE 114
            |....|::|:|:.::|:...::||.:::.||.||||:|.||||:|.::..::|:.|..:..||||
Human   221 ADRAFLQLERKFGRMRRLHMQRRSFIIQNIPGFWVTAFRNHPQLSPMISGQDEDMLRYMINLEVE 285

  Fly   115 EFEDIKSGYRINFHFDENPYFENKVLTKEFHLNSAAASENGDWPASTSTPIKWKEGKNLLKLLLT 179
            |.:..::|.:..|.|..||||.|:.|.||:...|:..      ..|.||||:|..|::      .
Human   286 ELKHPRAGCKFKFIFQGNPYFRNEGLVKEYERRSSGR------VVSLSTPIRWHRGQD------P 338

  Fly   180 KPYGNKKKRNSEYKTFFDWFSDNTDPVNDEIAELIKDDLWPNPLQYYLV 228
            :.:.::.:..:...:||:||||::....|.|||:||.:||||||||||:
Human   339 QAHIHRNREGNTIPSFFNWFSDHSLLEFDRIAEIIKGELWPNPLQYYLM 387

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SetNP_650438.2 NAP 31..227 CDD:279323 68/195 (35%)
TSPYL4NP_067680.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..129
NAP 207..386 CDD:279323 68/190 (36%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 391..414
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165152048
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1508
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1191764at2759
OrthoFinder 1 1.000 - - FOG0000644
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11875
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
76.810

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