DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Set and Tspyl1

DIOPT Version :9

Sequence 1:	NP_650438.2	Gene:	Set / 41844	FlyBaseID:	FBgn0014879	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_033459.1	Gene:	Tspyl1 / 22110	MGIID:	1298395	Length:	379	Species:	Mus musculus

Alignment Length:	249	Identity:	84/249 - (33%)
Similarity:	127/249 - (51%)	Gaps:	48/249 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 APADGNTSAAAGNNE----------EESEALE------------------------QIDACQNEI 43
            |.|:.:..|..|:.|          ||.|.||                        .::|.|.|:
Mouse   117 AAAEKSEVATPGSEEVMEVEQKPAGEEMEMLEASGGVREAPEEAGPWHLGIDLRRNPLEAIQLEL 181

  Fly    44 DALNEKASEEILKVEQKYNKLRKPCYEKRSELVKRIPNFWVTSFINHPQVSGILDEEEEECLHAL 108
            |.:|.:|......:|||:.::|:...|:|:.:::.||.||:|:|.||||:|.::...:.|.|..:
Mouse   182 DTVNAQADRAFQHLEQKFGRMRRHYLERRNYIIQNIPGFWMTAFRNHPQLSAMIRGRDAEMLRYV 246

  Fly   109 NKLEVEEFEDIKSGYRINFHFDENPYFENKVLTKEFHLNSAAASENGDWPASTSTPIKWKEGKNL 173
            ..|||:|....|:|.:..|.|..||||.||::.||:.:.|:..      ..|.||||.|:.|.
Mouse   247 TSLEVKELRHPKTGCKFKFFFRRNPYFRNKLIVKEYEVRSSGR------VVSLSTPIIWRRGH-- 303

  Fly   174 LKLLLTKPYGNKKKRNSEYKTFFDWFSDNTDPVNDEIAELIKDDLWPNPLQYYL 227
                  :|....::......:||.||||::.|.:|.|||:||:|||||||||||
Mouse   304 ------EPQSFIRRNQDLICSFFTWFSDHSLPESDRIAEIIKEDLWPNPLQYYL 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Set	NP_650438.2	NAP	31..227	CDD:279323	75/219 (34%)
Tspyl1	NP_033459.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..58
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	97..134		5/16 (31%)
		NAP	174..351	CDD:298680	72/190 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842144
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1508
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1191764at2759
OrthoFinder	1	1.000	-	-		FOG0000644
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11875
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.810