DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Set and Nap1l2

DIOPT Version :9

Sequence 1:	NP_650438.2	Gene:	Set / 41844	FlyBaseID:	FBgn0014879	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_032697.2	Gene:	Nap1l2 / 17954	MGIID:	106654	Length:	460	Species:	Mus musculus

Alignment Length:	274	Identity:	67/274 - (24%)
Similarity:	113/274 - (41%)	Gaps:	77/274 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 DGNTSAAAGNNEEESEALEQIDACQNEIDALNEKASEEILKVEQKYNKLRKPCYEKRSELVKRIP 80
            ||........::||.|        :.|.|:......||:                 ..|..|.||
Mouse   202 DGYEDCYYDYDDEEEE--------EEEDDSAGATGGEEV-----------------NEEDPKGIP 241

  Fly    81 NFWVTSFINHPQVSGILDEEEEECLHALNKLEVEEFEDIKS-GYRINFHFDENPYFENKVLTKEF 144
            :||:|...|...::.::.:.:|..|..|..::|:..:..:. .:.:.|||..|.||:|::|||.:
Mouse   242 DFWLTVLKNVEALTPMIKKYDEPILKLLTDIKVKLSDPGEPLSFTLEFHFKPNEYFKNELLTKTY 306

  Fly   145 HLNSAAASENGDWP---------ASTSTPIKWKEGKNL-LKLLLTKPYGNKKKRNSEYKT----- 194
            .|.|..|..:   |         .:|...|.|.||||: |:.:      .||:|:..:.|
Mouse   307 VLKSKLACYD---PHPYRGTAIEYATGCDIDWNEGKNVTLRTI------KKKQRHRVWGTVRTVT 362

  Fly   195 -------FFDWFSDNTDPVN--DEIAELIKDD-LWPNPLQYYLVP---------DIEVEPED--- 237
                   ||::||.:...:|  ||     .|| |..:.|:.|::|         .:|.:.|.
Mouse   363 EDFPKDSFFNFFSPHGISLNGGDE-----NDDFLLGHNLRTYIIPRSVLFFSGDALESQQEGVVR 422

  Fly   238 EEDNEDNDEEAFDD 251
            |.::|..|:..:||
Mouse   423 EVNDEIYDKIIYDD 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Set	NP_650438.2	NAP	31..227	CDD:279323	54/221 (24%)
Nap1l2	NP_032697.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..87
		NAP	111..410	CDD:279323	60/246 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	213..238		8/49 (16%)
		Nuclear localization signal. /evidence=ECO:0000255	346..352		2/11 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842141
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840