DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eIF2gamma and AT4G18330

DIOPT Version :9

Sequence 1:	NP_001262587.1	Gene:	eIF2gamma / 41843	FlyBaseID:	FBgn0263740	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_974567.1	Gene:	AT4G18330 / 827559	AraportID:	AT4G18330	Length:	471	Species:	Arabidopsis thaliana

Alignment Length:	460	Identity:	318/460 - (69%)
Similarity:	370/460 - (80%)	Gaps:	5/460 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 IGVNRNLQKQDLSNLDVSKLTPLSPEVISRQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNEL 72
            |..|:.|.:|||:.|||:||.||.||||||||||||||||||||||||:||||||||||||||||
plant     7 ISRNKGLAEQDLTKLDVTKLHPLFPEVISRQATINIGTIGHVAHGKSTIVKAISGVQTVRFKNEL 71

  Fly    73 ERNITIKLGYANAKIYKCDNPKCPRPASFVSDASSKDDSLPCT---RLNCSGNFRLVRHVSFVDC 134
            ||||||||||||||||||::.|||||..:.|..|.|:|:..|.   ..||....|  ||||.|||
plant    72 ERNITIKLGYANAKIYKCEDDKCPRPMCYKSYGSGKEDNPTCDVPGFENCKMTLR--RHVSCVDC 134

  Fly   135 PGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKQILILQNKIDLIKESQA 199
            |||||||||||||||::|.||||||.|||||||||:||||::::|:||.|:|||||||||.|..|
plant   135 PGHDILMATMLNGAAIVDGALLLIAANESCPQPQTAEHLASVDMMRLKHIIILQNKIDLINEKAA 199

  Fly   200 KEQYEEITKFVQGTVAEGAPIIPISAQLKYNIDVLCEYIVNKIPVPPRDFNAPPRLIVIRSFDVN 264
            .||:|.|.||:..|.||.|||:|:||||||||||:.||||.|||:|.|||.:||::|||||||||
plant   200 TEQHEAIQKFITNTNAEDAPIVPVSAQLKYNIDVVSEYIVKKIPIPVRDFVSPPKMIVIRSFDVN 264

  Fly   265 KPGCEVADLKGGVAGGSILSGVLKVGQEIEVRPGVVTKDSDGNITCRPIFSRIVSLFAEQNELQY 329
            |||....::||||||||||.|||||.|.||:|||:..||..||..|.||:|||.||:|||||||:
plant   265 KPGSAGHEMKGGVAGGSILQGVLKVNQLIEIRPGITGKDEHGNSKCTPIYSRITSLYAEQNELQF 329

  Fly   330 AVPGGLIGVGTKIDPTLCRADRLVGQVLGAVGQLPDIYQELEISYYLLRRLLGVRTDGDKKGARV 394
            |||||||||||.:||||.|||||||||||.:|.|||::.|||:||.||.||:||||...:|..:|
plant   330 AVPGGLIGVGTTMDPTLTRADRLVGQVLGEMGTLPDVFVELEVSYQLLTRLIGVRTKEKEKQMKV 394

  Fly   395 EKLQKNEILLVNIGSLSTGGRISATKGDLAKIVLTTPVCTEKGEKIALSRRVENHWRLIGWGQIF 459
            .||.|.|||:|||||:|||.::...|.|:.|:.||:||||..|||:||||||:.||||||.|||.
plant   395 SKLTKEEILMVNIGSMSTGAKVIGVKKDMVKLQLTSPVCTTIGEKVALSRRVDRHWRLIGKGQIM 459

  Fly   460 GGKTI 464
            .|.||
plant   460 AGTTI 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF2gamma	NP_001262587.1	PTZ00327	11..465	CDD:240362	317/457 (69%)
AT4G18330	NP_974567.1	PTZ00327	6..464	CDD:240362	316/458 (69%)
		eIF2_gamma	40..247	CDD:206675	150/208 (72%)
		eIF2_gamma_II	248..361	CDD:293889	82/112 (73%)
		eIF2_gamma_III	364..458	CDD:294011	56/93 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	308	1.000	Domainoid score	I318
eggNOG	1	0.900	-	-		E1_COG3276
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	659	1.000	Inparanoid score	I159
OMA	1	1.010	-	-		QHG62159
OrthoDB	1	1.010	-	-		D903135at2759
OrthoFinder	1	1.000	-	-		FOG0002790
OrthoInspector	1	1.000	-	-		otm2743
orthoMCL	1	0.900	-	-		OOG6_101121
Panther	1	1.100	-	-	O	PTHR42854
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1879
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840