Protein Alignment eIF2gamma and 42sp50

DIOPT Version :10

• Sequence 1: NP_731993.1
• Gene: eIF2gamma / 41843
• FlyBaseID: FBgn0263740
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_001011438.1
• Gene: 42sp50 / 496924
• XenbaseID: XB-GENE-5853280
• Length: 463
• Species: Xenopus tropicalis
• Alignment Length: 504
• Identity: 107/504 - (21%)
• Similarity: 164/504 - (32%)
• Gaps: 181/504 - (35%)

  Fly    27 LTPLSPEVISRQATINIGTIGHVAHGKSTVV------------KAISGVQTV------------- 66
            :|..:|:    :..:|:..||||..||||..            :|:..|:..
 Frog     1 MTDKTPQ----KTHLNVVIIGHVDSGKSTTTGHLIYKCGGFDPRALEKVEAAAAQLGKGSFKFAW 61

  Fly    67 ---RFKNELERNITIKLGYANAKIYKCDNPKCPRPASFVSDASSKDDSLPCTRLNCSGNFRLVRH 128
               :.|.|.||.|||.:     .::|                                 |:..|.
 Frog    62 ILDKLKAERERGITIDI-----SLWK---------------------------------FQTNRF 88

  Fly   129 -VSFVDCPGHDILMATMLNGAAVMDAALLLIAGNES------CPQPQTSEHLAAIEIMKLKQILI 186
             ::.:|.|||...:..|:.|.:..|.|||:::....      ....||.||......|.:||:::
 Frog    89 TITIIDAPGHRDFIKNMITGTSQADVALLVVSAATGEFEAGVSRNGQTREHALLAYTMGVKQMIV 153

  Fly   187 LQNKIDLIKESQAKEQYEEITKFVQ------GTVAEGAPIIPISAQLKYNI-------------- 231
            ..||:||.....:.::::|:.:.|.      |......|.:|:|.....||
 Frog   154 CVNKMDLTDPPYSHKRFDEVVRNVTVYLKKIGYNPTTIPFVPVSGWTGENISSPSQKMGWFKGWK 218

  Fly   232 ----------DVLCEYIVNKIPVPPRDFNAPPRLIVIRSFDVNKPGCEVADLKGGVAGGSILSGV 286
                      ..|.|.:...:| |.|..|.|.||.:   .||.|.|.     .|.|..|.|.:|:
 Frog   219 VKRKDGFTKGQSLLEVLDALVP-PVRPANKPLRLPL---QDVYKIGG-----IGTVPVGKIETGI 274

  Fly   287 LKVGQEIEVRPGVVTKDSDGNITCRPIFSRIVSLFAEQNELQYAVPG-----------------G 334
            ||.|..|...|.             ...:.:.|:......||.|.||                 |
 Frog   275 LKPGMTITFAPS-------------GFAAEVKSIEMHHEPLQTAFPGFNVGFNVKNIAVKSLKRG 326

  Fly   335 LIGVGTKIDPTLCRADRLVGQVL-----GAV--GQLPDI---YQELEISYYLLRRLLGVRTDGDK 389
            .:...:|.||. ..|.....||:     |.:  |..|.|   ...:...:..|:..:..||.
 Frog   327 NVAGNSKSDPP-TEASSFTAQVIILNHPGLIKAGYSPVIDCHTAHITCQFTELQEKIDRRTG--- 387

  Fly   390 KGARVEKLQKNEILLVNIGSLSTGGRISATKGDLAKIVL--TTPVCTEK 436
                 :||:.|..:|              ..||.|.|.|  ..|.|.|:
 Frog   388 -----KKLEDNPGVL--------------KSGDAAIITLKPIKPFCVER 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2gamma	NP_731993.1	PTZ00327	11..465	CDD:240362	107/504 (21%)
42sp50	NP_001011438.1	P-loop containing Nucleoside Triphosphate Hydrolases	7..447	CDD:476819	105/498 (21%)