Protein Alignment eIF2gamma and eef1a2

DIOPT Version :10

• Sequence 1: NP_731993.1
• Gene: eIF2gamma / 41843
• FlyBaseID: FBgn0263740
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_001011418.1
• Gene: eef1a2 / 496898
• XenbaseID: XB-GENE-975439
• Length: 463
• Species: Xenopus tropicalis
• Alignment Length: 365
• Identity: 82/365 - (22%)
• Similarity: 132/365 - (36%)
• Gaps: 123/365 - (33%)

  Fly    41 INIGTIGHVAHGKST----VVKAISGV--QTV----------------------RFKNELERNIT 77
            |||..||||..||||    ::....|:  :|:                      :.|.|.||.||
 Frog     8 INIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGIT 72

  Fly    78 IKLGYANAKIYKCDNPKCPRPASFVSDASSKDDSLPCTRLNCSGNFRLVRHVSFVDCPGHDILMA 142
            |.:     .::|.:..|                                .:::.:|.|||...:.
 Frog    73 IDI-----SLWKFETNK--------------------------------YYITIIDAPGHRDFIK 100

  Fly   143 TMLNGAAVMDAALLLIAGNES------CPQPQTSEHLAAIEIMKLKQILILQNKIDLIKESQAKE 201
            .|:.|.:..|.|:|::|....      ....||.||......:.:||:::..||:|..:...:::
 Frog   101 NMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGINKMDSTEPPYSEK 165

  Fly   202 QYEEITKFVQGTVAE------GAPIIPISA------------------------QLKYNIDVLCE 236
            :|:||.|.|...:.:      ..|.:|||.                        :...|...|.|
 Frog   166 RYDEIVKEVSAYIKKIGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNANGVSLLE 230

  Fly   237 YIVNKIPVPPRDFNAPPRLIVIRSFDVNKPGCEVADLKGGVAGGSILSGVLKVGQEIEVRPGVVT 301
            .:...:| |.|..:.|.||.:   .||.|.|.     .|.|..|.:.:|:||        ||:|.
 Frog   231 ALDTILP-PTRPTDKPLRLPL---QDVYKIGG-----IGTVPVGRVETGILK--------PGMVV 278

  Fly   302 KDSDGNITCRPIFSRIVSLFAEQNELQYAVPGGLIGVGTK 341
            ..:..|||     :.:.|:......|..|:||..:|...|
 Frog   279 TFAPVNIT-----TEVKSVEMHHEALSEALPGDNVGFNVK 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2gamma	NP_731993.1	PTZ00327	11..465	CDD:240362	82/365 (22%)
eef1a2	NP_001011418.1	PTZ00141	1..460	CDD:185474	82/365 (22%)