Protein Alignment eIF2gamma and mEFTu1

DIOPT Version :10

• Sequence 1: NP_731993.1
• Gene: eIF2gamma / 41843
• FlyBaseID: FBgn0263740
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_524752.1
• Gene: mEFTu1 / 44438
• FlyBaseID: FBgn0024556
• Length: 489
• Species: Drosophila melanogaster
• Alignment Length: 461
• Identity: 115/461 - (24%)
• Similarity: 183/461 - (39%)
• Gaps: 105/461 - (22%)

  Fly    42 NIGTIGHVAHGKSTVVKAISGV----QTVRFK--NELE-------RNITIKLGYANAKIYKCDNP 93
            |:||||||.|||:|:..||:.|    |....|  ||::       |.|||.:.:..   |:.:
  Fly    84 NVGTIGHVDHGKTTLTAAITKVLADKQLAESKKYNEIDNAPEEKARGITINVAHVE---YQTE-- 143

  Fly    94 KCPRPASFVSDASSKDDSLPCTRLNCSGNFRLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLI 158
                                            .||....|||||...:..|:.|.|.||.|:|::
  Fly   144 --------------------------------TRHYGHTDCPGHADYIKNMITGTAQMDGAILVV 176

  Fly   159 AGNESCPQPQTSEHLAAIEIMKLKQILILQNKIDLIKESQAKEQYEEITKFV--QGTVAEGAPII 221
            |..:.. .|||.||:...:.:.:..|::..||:|...|........||.:.:  .|...:..|::
  Fly   177 AATDGA-MPQTREHMLLAKQIGIDHIVVFINKVDAADEEMVDLVEMEIRELLTEMGYDGDKIPVV 240

  Fly   222 PISAQL----------KYNIDVLCEYIVNKIPVPPRDFNAPPRLIVIRSFDVNKPGCEVADLKGG 276
            ..||..          |..|..|.:.:.:.||.|.|:.:.|..|.|...:.:  ||      :|.
  Fly   241 KGSALCALEDKSPEIGKEAILKLLQEVDSFIPTPVRELDKPFLLPVENVYSI--PG------RGT 297

  Fly   277 VAGGSILSGVLKVGQEIE-VRPGVVTKDSDGNITCRPIFSRIVSLFAEQNELQYAVPGGLIGV-- 338
            |..|.:..||:|.|.|.| |....|.|.:   :|...:|.:|         |:.|..|..:|.
  Fly   298 VVTGRLERGVVKKGMECEFVGYNKVLKST---VTGVEMFHQI---------LEEAQAGDQLGALV 350

  Fly   339 -GTKIDPTLCRADRLVGQVLGAVGQLPDIYQELEISYYLLRRLLGVRTDGDKKGARVEKLQKNEI 402
             |.|      |.|...|.|:...|.:..: .:||...|:|.:..|.||.......:::...:...
  Fly   351 RGVK------RDDIKRGMVMCKPGSVKAL-DQLEAQVYILSKDEGGRTKPFMSFIQLQMFSRTWD 408

  Fly   403 LLVNIGSLSTGGRISATKGDLAKIV--LTTPVCTEKGEKIALSRRVENHWRLIGWGQIFGGKTIT 465
            ..|.:   ....:.....|:..|::  |..|:..|:|::..|  |..|  ..:|.|.:  ..|:.
  Fly   409 CAVQV---QIPDKEMVMPGEDTKLILRLIRPMVLEQGQRFTL--RDGN--LTLGTGVV--TSTLP 464

  Fly   466 PVLDSQ 471
            |:.:||
  Fly   465 PLTESQ 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2gamma	NP_731993.1	PTZ00327	11..465	CDD:240362	112/453 (25%)
mEFTu1	NP_524752.1	TufA	73..460	CDD:439820	111/449 (25%)