Protein Alignment eIF2gamma and si:dkey-37o8.1

DIOPT Version :9

• Sequence 1: NP_001262587.1
• Gene: eIF2gamma / 41843
• FlyBaseID: FBgn0263740
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_001157466.1
• Gene: si:dkey-37o8.1 / 407641
• ZFINID: ZDB-GENE-030131-5667
• Length: 458
• Species: Danio rerio
• Alignment Length: 460
• Identity: 109/460 - (23%)
• Similarity: 178/460 - (38%)
• Gaps: 119/460 - (25%)

  Fly    41 INIGTIGHVAHGKST----VVKAISGVQTVRFKNELERNITIKLGYANAK-IYKCDNPKCPRPAS 100
            ||:..||||..||||    :|....|:.. |...:.|:..| ::|.::.| .:..|..|..|...
Zfish     8 INLVIIGHVDGGKSTTTGHLVYKCGGIDH-RTIEKYEKAAT-QMGKSSFKYAWVLDKLKAERERG 70

  Fly   101 FVSDASSKDDSLPCTRLNCSGNFRLVRHV-SFVDCPGHDILMATMLNGAAVMDAALLLIAGNES- 163
            ...|.|..             .|...::. :.:|.|||...:..|:.|.:..|||||:::..:.
Zfish    71 ITIDISLL-------------KFNTQKYTFTIIDAPGHRDFIKNMITGTSQADAALLIVSAAKGE 122

  Fly   164 -----CPQPQTSEHLAAIEIMKLKQILILQNKIDLIKESQAKEQYEEITK----FVQ--GTVAEG 217
                 ....||.||......:.:||:::..||:||.:...::::|:|:.:    ||:  |.....
Zfish   123 FEAGISRNGQTREHALLAYTLGVKQLVVCVNKMDLTEPPFSQKRYDEVVRNVSVFVKKIGFEIGA 187

  Fly   218 APIIPISAQLKYNIDV------------------------LCEYIVNKIPVPPRDFNAPPRLIVI 258
            .|.||||.....|:.|                        |.| :::.:..|.|:...|.||.:
Zfish   188 VPFIPISGWSGENMIVPSQKMQWFKGWKLKRKEGHCHGRTLLE-VLDSLHPPVRNAGKPLRLPL- 250

  Fly   259 RSFDVNKPGCEVADLKGGVAGGSILSGVLKVGQEIEVRPGVVTKDSDGNITCRPIFSRIVSLFAE 323
              .||.|.|.     .|.|..|.|.:||||        ||:|...|...:|     :.:.|:...
Zfish   251 --QDVYKIGG-----VGTVPVGKIETGVLK--------PGMVLTFSPAKLT-----AEVKSIEMH 295

  Fly   324 QNELQYAVPGGLIGVGTKIDPTLCRADRLVGQVLGAVGQLP--DIYQ------------ELEISY 374
            ...||.|:||..:|...| :.::....|  |.|.|...|.|  |:..            ::::.|
Zfish   296 HQGLQTALPGHNVGFNIK-NVSVKNLRR--GDVAGNAQQDPPSDVSSFIAQIIMLNHPGKIKVGY 357

  Fly   375 ---------YLLRRLLGVRTDGDKKGARVEKLQKNEILLVNIGSLSTGGRISATKGDLAKIVLTT 430
                     ::..|...:|...|::..|  ||:            |....:.:..|...|:|...
Zfish   358 SPVLDCHTTHVSCRFAELREKLDRRSGR--KLE------------SWPQYLRSGDGATVKLVPNK 408

  Fly   431 PVCTE 435
            |:|.|
Zfish   409 PLCVE 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2gamma	NP_001262587.1	PTZ00327	11..465	CDD:240362	109/460 (24%)
si:dkey-37o8.1	NP_001157466.1	PTZ00141	1..458	CDD:185474	109/460 (24%)
		EF1_alpha	9..239	CDD:206670	57/245 (23%)
		EF1_alpha_II	244..332	CDD:293894	32/111 (29%)
		EF1_alpha_III	337..438	CDD:294004	14/91 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592501
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840