Protein Alignment eIF2gamma and CG2017

DIOPT Version :10

• Sequence 1: NP_731993.1
• Gene: eIF2gamma / 41843
• FlyBaseID: FBgn0263740
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_649603.3
• Gene: CG2017 / 40733
• FlyBaseID: FBgn0037391
• Length: 643
• Species: Drosophila melanogaster
• Alignment Length: 665
• Identity: 113/665 - (16%)
• Similarity: 195/665 - (29%)
• Gaps: 252/665 - (37%)

  Fly   343 LGKFGHEELTKKLAEAEDKRESLNIEIEEIEHVQLKALRKKYEKLTKELRNEEEEKFNTRGKIAT 407
            ||:...|.|:.:.|.:..:|.         ||...::....|....     ::|.||::..:
  Fly    65 LGRSAAESLSAQEAASSSERG---------EHTNSRSPSTSYSSCI-----DDERKFSSPHR--- 112

  Fly   408 LRRTIEQDQKILRSMKATKKNDVNKFGPYMSEILTEIDHR---------------SSQFKQKPKG 457
             ||.::.......::..|:..:.::..|..|::..|...|               ||....|.||
  Fly   113 -RRVVDVSDHKTCALLMTRMKEASRQLPSPSQLAAEEARREQKAESGTFVRKTTLSSNAPVKEKG 176

  Fly   458 PLGKYV------------TLVEPKWACATEECFKNIANNFLCCSQEDAATLRKIFDILKIPSNDR 510
            |...::            .::|  |..........|..|.:..|.|.           .:|.||:
  Fly   177 PSSLFIFAEDNIIRRNAKAIIE--WGPFEYFILLTIIGNCVVLSMEQ-----------HLPKNDK 228

  Fly   511 PTI------VVSRFTGIKYEDLQQPGYQFKTLYRTLAFSDVDVHNAIIDKS--NCEQFLLIEDKT 567
            ..:      ....|.||         :..:.:.:.:||. ..:|.....:|  |...|:::....
  Fly   229 KALSEWLERTEPYFMGI---------FCLECVLKVIAFG-FALHKGSYLRSGWNIMDFIVVVSGV 283

  Fly   568 AAM-------------------------------KLMG-------------CDDPPKYAVKAYTP 588
            ..|                               ||:.             |...|...:.....
  Fly   284 VTMLPFSPATQTANQPVDSVDLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVL 348

  Fly   589 DASQIFA-NGLHSQYRFYSSRGKRAVGLFGVNQKQVDEETLEQELEAANR-ELIRLENHDIK--- 648
            .|..||| .||    .|||.....|.    .|::...|...|:.:...|: ..:.:.|.|:|
  Fly   349 FAIIIFAIIGL----EFYSGAFHSAC----YNERGEIENVSERPMPCTNKTSPMGVYNCDVKGTT 405

  Fly   649 LIEKTLRELTMERSTIKSTIDKLDKKTRELQYERVKIDRNINDWKADMTQCANTEQVDNI----N 709
            .::|.:..                      .|.....| ||......:.||...|....:    |
  Fly   406 CLQKWIGP----------------------NYGITSFD-NIGFAMITVFQCITMEGWTTVMYYTN 447

  Fly   710 DALGE------------------LQEKLSILEEEAYCIQDKLDELDEKFQPAIKTKNESEKNYVE 756
            |:||.                  |...|.:|..|....:::::...|    .:|.:.:.     :
  Fly   448 DSLGSTYNWAYFIPLIVLGSFFMLNLVLGVLSGEFAKERERVENRRE----FLKLRRQQ-----Q 503

  Fly   757 LQQEVKGYAAQTLSFQKQLRKLDEDGEAGKNRLDKLKSNEDELYHDEARLKSERDEALNIVEKEK 821
            :::|:.||....|:                              .:|..||.:|     ..|:||
  Fly   504 IERELNGYLEWILT------------------------------AEEVILKEDR-----TTEEEK 533

  Fly   822 VTIERPRREADPPDLSEFPSTKDARKKIIEMHKAISRDAAECGDTVTIGSVKEFKENLKKLRESC 886
            ..|...||.|             |.||:.:..|..|.:..|           :|:|      :..
  Fly   534 AAIMEARRRA-------------ANKKLKQASKQQSTETEE-----------DFEE------DED 568

  Fly   887 RMLEEVVEEMQTVHN 901
            .|.||.|:|..||.:
  Fly   569 EMEEEYVDEGGTVED 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2gamma	NP_731993.1	PTZ00327	11..465	CDD:240362	25/148 (17%)
CG2017	NP_649603.3	GTPBP1_like	217..436	CDD:206728	43/270 (16%)
		GTPBP_II	450..536	CDD:293895	19/129 (15%)
		GTPBP_III	547..634	CDD:294007	13/54 (24%)