Protein Alignment eIF2gamma and eef1a1l1

DIOPT Version :9

• Sequence 1: NP_001262587.1
• Gene: eIF2gamma / 41843
• FlyBaseID: FBgn0263740
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_571338.1
• Gene: eef1a1l1 / 30516
• ZFINID: ZDB-GENE-990415-52
• Length: 462
• Species: Danio rerio
• Alignment Length: 484
• Identity: 105/484 - (21%)
• Similarity: 169/484 - (34%)
• Gaps: 167/484 - (34%)

  Fly    41 INIGTIGHVAHGKST----VVKAISGV--QTV----------------------RFKNELERNIT 77
            |||..||||..||||    ::....|:  :|:                      :.|.|.||.||
Zfish     8 INIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGIT 72

  Fly    78 IKLGYANAKIYKCDNPKCPRPASFVSDASSKDDSLPCTRLNCSGNFRLVRHVSFVDCPGHDILMA 142
            |.:.     ::|.:..|                                .:|:.:|.|||...:.
Zfish    73 IDIA-----LWKFETSK--------------------------------YYVTIIDAPGHRDFIK 100

  Fly   143 TMLNGAAVMDAALLLIAGNES------CPQPQTSEHLAAIEIMKLKQILILQNKIDLIKESQAKE 201
            .|:.|.:..|.|:|::||...      ....||.||......:.:||:::..||:|..:...::.
Zfish   101 NMITGTSQADCAVLIVAGGVGEFEAGISKNGQTREHALLAFTLGVKQLIVGVNKMDSTEPPYSQA 165

  Fly   202 QYEEITKFVQGTVAE------GAPIIPISAQLKYNIDVLCEYIVN-------------------- 240
            ::|||||.|...:.:      ....:|||.   ::.|.:.|...|
Zfish   166 RFEEITKEVSAYIKKIGYNPASVAFVPISG---WHGDNMLEASSNMGWFKGWKIERKEGNASGTT 227

  Fly   241 ------KIPVPPRDFNAPPRLIVIRSFDVNKPGCEVADLKGGVAGGSILSGVLKVGQEIEVRPGV 299
                  .|..|.|..:.|.||.:   .||.|.|.     .|.|..|.:.:||||        ||:
Zfish   228 LLDALDAILPPSRPTDKPLRLPL---QDVYKIGG-----IGTVPVGRVETGVLK--------PGM 276

  Fly   300 VTKDSDGNITCRPIFSRIVSLFAEQNELQYAVPGGLIGVG-----------------TKIDPTLC 347
            |...:..|:|     :.:.|:......|..|.||..:|..                 :|.||.:
Zfish   277 VVTFAPANVT-----TEVKSVEMHHESLTEATPGDNVGFNVKNVSVKDIRRGNVAGDSKNDPPM- 335

  Fly   348 RADRLVGQV--LGAVGQLPDIYQELEISY--YLLRRLLGVRTDGDKKGARVEKLQKNEILLVNIG 408
            .|.....||  |...||:...|..:...:  ::..:...::...|::..:  ||:.|...|
Zfish   336 EAANFNAQVIILNHPGQISQGYAPVLDCHTAHIACKFAELKEKIDRRSGK--KLEDNPKAL---- 394

  Fly   409 SLSTGGRISATKGDLA--KIVLTTPVCTE 435
                      ..||.|  ::|...|:|.|
Zfish   395 ----------KSGDAAIVEMVPGKPMCVE 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2gamma	NP_001262587.1	PTZ00327	11..465	CDD:240362	105/484 (22%)
eef1a1l1	NP_571338.1	PTZ00141	1..460	CDD:185474	105/484 (22%)
		G1. /evidence=ECO:0000250	14..21		4/6 (67%)
		G2. /evidence=ECO:0000250	70..74		2/3 (67%)
		G3. /evidence=ECO:0000250	91..94		1/2 (50%)
		G4. /evidence=ECO:0000250	153..156		2/2 (100%)
		G5. /evidence=ECO:0000250	194..196		1/4 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592514
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840