DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42404 and dgcr2

DIOPT Version :9

Sequence 1:	NP_001247118.1	Gene:	CG42404 / 41842	FlyBaseID:	FBgn0259823	Length:	1133	Species:	Drosophila melanogaster
Sequence 2:	NP_001002656.1	Gene:	dgcr2 / 436929	ZFINID:	ZDB-GENE-040718-404	Length:	536	Species:	Danio rerio

Alignment Length:	209	Identity:	62/209 - (29%)
Similarity:	88/209 - (42%)	Gaps:	59/209 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 SCRDYNGKMYETGMHYMP-GPDSCRLCICDSGLPKACKMVLCEAFSKCKSFQTVGSGNNCCEVIC 91
            :|.|....:...|.::.| |.|.|..|.|..|.|:.|...|||....|:.|:.  ....||:..|
Zfish   266 TCVDIKDNVVNEGYYFTPKGDDPCLSCTCHDGEPEMCVAALCERPQGCQHFRK--DPKECCKFTC 328

  Fly    92 LDDQFSDGSTDF-----GIXLVASGITATLSLSLLFFLVNRLRQRKMRARENRQNAEDQRSIVGS 151
            ||   .|||:.|     |:.|:.|.|::.|.||||.|:|:|||||:      |:..|   :::|
Zfish   329 LD---PDGSSLFDSMASGMRLIVSCISSFLILSLLLFMVHRLRQRR------RERIE---TLIG- 380

  Fly   152 IGYIAGNMGYMEGNLS----AIDY----------------SYSGAATHYPLWKP----------H 186
                 ||:.:.  ||.    ..||                ...|.|.|:....|          |
Zfish   381 -----GNLHHF--NLGRRVPGFDYRPDAFGTGLTPLHLSDDGEGGAFHFQEPPPPYAAYKYPDIH 438

  Fly   187 FPRGEAPPPYEEAV 200
            .| .:.|||||.::
Zfish   439 HP-DDPPPPYEASI 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42404	NP_001247118.1	VWC	32..89	CDD:214564	17/57 (30%)
dgcr2	NP_001002656.1	LDLa	40..76	CDD:238060
		CLECT_DGCR2_like	109..263	CDD:153069
		VWC	267..325	CDD:214564	18/59 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008412
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15256
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.100