DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Amt and MEP3

DIOPT Version :9

Sequence 1:	NP_001097800.1	Gene:	Amt / 41841	FlyBaseID:	FBgn0038309	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_015464.1	Gene:	MEP3 / 856260	SGDID:	S000006342	Length:	489	Species:	Saccharomyces cerevisiae

Alignment Length:	443	Identity:	118/443 - (26%)
Similarity:	197/443 - (44%)	Gaps:	63/443 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 YDLSVEDTNWVLTSSFIIFTMQTGFGMLESGCVSIKNEVNIMMKNVIDIVLGGFTYWLFGYGMSF 85
            ||.|.  ..:::..:.::|.|..|.|.|.||....|:.:.::...::..::|...::.:||.::|
Yeast    13 YDSST--VAFMILGAALVFFMVPGLGFLYSGLARRKSALALIWVVIMATLVGILQWYFWGYSLAF 75

  Fly    86 GRGPLSNPFIA-------------IGDFLLDPPVGDALMGQIFAAFLFQLSFATTATTIVSGAMA 137
            .:...:|.||.             |.|        |:...::..| :||:.|...|.:|::||.|
Yeast    76 SKTATNNKFIGNLDSFGFRNVYGKISD--------DSTYPELIYA-IFQMMFMCVALSIIAGATA 131

  Fly   138 ERCNFKAYCLFSFL-NTAVYCIPAGWVWGEHGFLNKLGAVDIAGSGPVHLIGGASAFASAAMLGP 201
            ||.....:.:|.|: .|.|||....|:|...|:..:.|.:|.||.|.:.::...:.|..:..||.
Yeast   132 ERGKLFPHMVFLFVFATLVYCPITYWIWAPGGWAYQWGVLDWAGGGNIEILSAVAGFVYSYFLGR 196

  Fly   202 RLGRYSEGYDPLPLGNPVNACMGLFVLWWGWLAFNSGSTYGVSGAKWQYAARAAVMTMMGSFGGG 266
            |.......:.|   .|.....:|..:||:|||.||:.|:...:    ..:..|.:.|.:.:..||
Yeast   197 RKENLLINFRP---HNVSMVTLGTSILWFGWLLFNAASSLSPN----MRSVYAFMNTCLSATTGG 254

  Fly   267 FTSSIYSF-----WRHGGGMDIMDLINGVLGSLVSIT--AGCF-LYRAWEALVIGAIGSLFCVLA 323
            .|..:..:     |...|      |.:|::..||:.|  :||. ||   .:|:.|.|..:.|..|
Yeast   255 MTWCLLDYRSEKKWSTVG------LCSGIICGLVAATPSSGCITLY---GSLIQGIIAGVVCNFA 310

  Fly   324 MPLFDRMGVDDPVGASAVHGVCGIWGVIAVGLF-ADNPIPLDTTNGRSGLFKGGGWYLLGIQTLS 387
            ..:...:.|||.:...|.||:.|:.|:|...|| ||..|.:|.|....|.:....|..:.||.
Yeast   311 TKIKYYLKVDDSLDLLAEHGIAGVVGLIFNALFAADWVIGMDGTTKHKGGWLTHNWKQMYIQI-- 373

  Fly   388 ALCLACWGVCS--TFLLLYVINKI--IPIRMDPHEELLGADLTEHRIRHSQIG 436
            |...|..|.|:  |.::.:|:.||  :.:|:....|.||.|       ..|||
Yeast   374 AYIGASAGYCAVVTAIICFVLGKIPGVHLRVTEEAEALGLD-------EDQIG 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Amt	NP_001097800.1	Ammonium_transp	30..428	CDD:275788	112/424 (26%)
MEP3	NP_015464.1	AmtB	13..430	CDD:223083	118/443 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346800
Domainoid	1	1.000	161	1.000	Domainoid score	I849
eggNOG	1	0.900	-	-		E1_COG0004
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	162	1.000	Inparanoid score	I1052
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001736
OrthoInspector	1	1.000	-	-		otm46755
orthoMCL	1	0.900	-	-		OOG6_100186
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X200
TreeFam	1	0.960	-	-
	10	9.650