Protein Alignment Amt and MEP2

DIOPT Version :9

• Sequence 1: NP_001097800.1
• Gene: Amt / 41841
• FlyBaseID: FBgn0038309
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_014257.1
• Gene: MEP2 / 855580
• SGDID: S000005086
• Length: 499
• Species: Saccharomyces cerevisiae
• Alignment Length: 525
• Identity: 144/525 - (27%)
• Similarity: 226/525 - (43%)
• Gaps: 82/525 - (15%)

  Fly    21 YDLSVEDTNWVLTSSFIIFTMQTGFGMLESGCVSIKNEVNIMMKNVIDIVLGGFTYWLFGYGMSF 85
            :||:  :..|:..:|..::.|..|.|:|.||....|:.::::..:::...:..|.::.:||.::|
Yeast    27 FDLA--NMGWIGVASAGVWIMVPGIGLLYSGLSRKKHALSLLWASMMASAVCIFQWFFWGYSLAF 89

  Fly    86 GRGPLSNPFIAIGDF-----LLDPPVGDALMGQIFAAFLFQLSFATTATTIVSGAMAERCNFKAY 145
            ......|.||...:|     :|..|...:.:..|..| ::|..||.....::.|...||......
Yeast    90 SHNTRGNGFIGTLEFFGFRNVLGAPSSVSSLPDILFA-VYQGMFAAVTGALMLGGACERARLFPM 153

  Fly   146 CLFSFL-NTAVYCIPAGWVWGEHGFLNKLGAVDIAGSGPVHLIGGASAFASAAMLGPRLGRYSEG 209
            .:|.|| .|.|||..|.|||...|:|.|||::|.||...|||..|......|.:||.|
Yeast   154 MVFLFLWMTIVYCPIACWVWNAEGWLVKLGSLDYAGGLCVHLTSGHGGLVYALILGKR------- 211

  Fly   210 YDP-----LPLGNP---VNACMGLFVLWWGWLAFNSGSTYGVSGAKWQYAARAAVMTMMGSFGGG 266
            .||     :|...|   .:..:|...||:||:.||.||....:...|.    :.:.|.:.:..||
Yeast   212 NDPVTRKGMPKYKPHSVTSVVLGTVFLWFGWMFFNGGSAGNATIRAWY----SIMSTNLAAACGG 272

  Fly   267 FTSSIYSFWRHGGGMDIMDLINGVLGSLVSITAGCFLYRAWEALVIGAIGSLFCVLAMPLFDRMG 331
            .|..:..::|.|.....:.|.:|::..||.||........|.|:|||.:....|.||:.|...:.
Yeast   273 LTWMVIDYFRCGRKWTTVGLCSGIIAGLVGITPAAGFVPIWSAVVIGVVTGAGCNLAVDLKSLLR 337

  Fly   332 VDDPVGASAVHGVCGIWGVIAVGLFADNPIPLDTTNGRSGLFKG---GGWY-----LLGIQTLSA 388
            :||.:...::|||.|..|.:..|:||     .|..|..:|.:..   |||.     .:|.| |:.
Yeast   338 IDDGLDCYSIHGVGGCIGSVLTGIFA-----ADYVNATAGSYISPIDGGWINHHYKQVGYQ-LAG 396

  Fly   389 LCLA-CWGVCSTFLLLYVINKI--IPIRMDPHEELLGADLTEHRIRHSQIGLSRAISALAPIKVD 450
            :|.| .|.|..|.:||..:|.|  :.:|:...||.||.|.       :|||......:.|.|...
Yeast   397 ICAALAWTVTVTSILLLTMNAIPFLKLRLSADEEELGTDA-------AQIGEFTYEESTAYIPEP 454

  Fly   451 LKDIAGIQPIGINPGHERSIDQLRAAEDKLQQWQSYLEQVSGSRANVKMDAGQSHADINFKPRTA 515
            ::.....|   :.|.|| :||      ||:                    .|.:.|:.|..|..|
Yeast   455 IRSKTSAQ---MPPPHE-NID------DKI--------------------VGNTDAEKNSTPSDA 489

  Fly   516 GNVFN 520
            .:..|
Yeast   490 SSTKN 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Amt	NP_001097800.1	Ammonium_transp	30..428	CDD:275788	123/422 (29%)
MEP2	NP_014257.1	AmtB	27..447	CDD:223083	128/446 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346801
Domainoid	1	1.000	161	1.000	Domainoid score	I849
eggNOG	1	0.900	-	-		E1_COG0004
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	162	1.000	Inparanoid score	I1052
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001736
OrthoInspector	1	1.000	-	-		otm46755
orthoMCL	1	0.900	-	-		OOG6_100186
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16229
SonicParanoid	1	1.000	-	-		X200
TreeFam	1	0.960	-	-
	11	10.680