Protein Alignment Amt and MEP1

DIOPT Version :10

• Sequence 1: NP_001097800.1
• Gene: Amt / 41841
• FlyBaseID: FBgn0038309
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_011636.3
• Gene: MEP1 / 853019
• SGDID: S000003353
• Length: 492
• Species: Saccharomyces cerevisiae
• Alignment Length: 531
• Identity: 132/531 - (24%)
• Similarity: 215/531 - (40%)
• Gaps: 104/531 - (19%)

  Fly    30 WVLTSSFIIFTMQTGFGMLESGCVSIKNEVNIMMKNVIDIVLGGFTYWLFGYGMSFGRGPLSNPF 94
            :::..:.::|.|..|.|.|.||....|:.:.::...::..::|...::.:||.::|.:...:|.|
Yeast    21 FMILGAALVFFMVPGLGFLYSGLARRKSALALIWVVLMATLVGILQWYFWGYSLAFSKSAPNNKF 85

  Fly    95 IA-IGDFLLDPPVG-----DALMGQIFAAFLFQLSFATTATTIVSGAMAERCNFKAYCLFSF-LN 152
            |. :..|......|     ||.....:|.  ||:.|:....:|::||.|||.....:.:|.| |.
Yeast    86 IGNLDSFGFRNVYGKKFDEDAYPELAYAT--FQMMFSCVNLSIIAGATAERGRLLPHMVFLFILA 148

  Fly   153 TAVYCIPAGWVWGEHGFLNKLGAVDIAGSGPVHLIGGASAFASAAMLGPRLGRYSEGYDPLPLGN 217
            |..||....|:|...|:..:.|.:|.||.|.:.::...|.|..:..||.|..:....:.|   .|
Yeast   149 TIGYCPVTYWIWSPGGWAYQWGVLDWAGGGNIEILSAVSGFVYSWFLGKRNEKLLINFRP---HN 210

  Fly   218 PVNACMGLFVLWWGWLAFNSGSTYGVSGAKWQYAARAAVMTMMGSFGGGFTSSIYSF-----WRH 277
            .....:|..:||:|||.|||.|:...:    ..:..|.:.|.:.:..||.|..:..:     |..
Yeast   211 VSLVTLGTSILWFGWLLFNSASSLSPN----LRSVYAFMNTCLSAITGGMTWCLLDYRSEKKWST 271

  Fly   278 GGGMDIMDLINGVLGSLVSIT--AGCF-LYRAWEALVIGAIGSLFCVLAMPLFDRMGVDDPVGAS 339
            .|      |.:|::..||:.|  :||. ||   .:|:.|.:..:.|..|..|.....|||.:...
Yeast   272 VG------LCSGIISGLVAATPSSGCITLY---GSLIQGIVAGVVCNFATKLKYYAKVDDAMDIL 327

  Fly   340 AVHGVCGIWGVIAVGLF-ADNPIPLDTTNGRSGLFKGGGWYLLGIQTL---SALCLACWGVCS-- 398
            |.|||.|:.|:|...|| ||..|.:|.|....     |||.....:.:   .|...|..|..:
Yeast   328 AEHGVAGVIGLIFNALFGADWVIGMDGTTEHE-----GGWVTHNYKQMYKQIAYIAASIGYTAAV 387

  Fly   399 TFLLLYVINKIIPIRMDPHEELLGADLTEHRIRHSQIGLSRAISALAPIKVDLKDIAGIQPIGIN 463
            |.::.:|:..|..:|:...||...|.:.|     .|||
Yeast   388 TAIICFVLGYIPGMRLRISEEAEEAGMDE-----DQIG--------------------------- 420

  Fly   464 PGHERSIDQLRAAEDKLQQWQSYLEQVSGSRANVKMDAGQSHADINFKPRTAGNVFNRRIPARKS 528
               |.:.|.:....|      .||..|         |.....:|:|.:      |.|..:.|.:|
Yeast   421 ---EFAYDYVEVRRD------YYLWGV---------DEDSQRSDVNHR------VNNAHLAAERS 461

  Fly   529 ISGGLYRSNNS 539
            .||    :|:|
Yeast   462 SSG----TNSS 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Amt	NP_001097800.1	AmtB	27..431	CDD:439775	112/421 (27%)
MEP1	NP_011636.3	amt	19..424	CDD:273292	116/460 (25%)