DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Amt and Rhcg

DIOPT Version :9

Sequence 1:	NP_001097800.1	Gene:	Amt / 41841	FlyBaseID:	FBgn0038309	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_062773.2	Gene:	Rhcg / 56315	MGIID:	1888517	Length:	498	Species:	Mus musculus

Alignment Length:	402	Identity:	87/402 - (21%)
Similarity:	146/402 - (36%)	Gaps:	84/402 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LSVEDTNWVLTSSFIIFTMQT-GFGMLESGCVSIKNEVN-------IMMKNVIDIVLGGFTY--- 76
            |.::.|..||...|:.:.:|. ....||....:|.::|.       ...::|..:|..||.:
Mouse    16 LILQVTMVVLFGVFVRYDIQADAHWWLEKKRKNISSDVENEFYYRYPSFQDVHAMVFVGFGFLMT 80

  Fly    77 WLFGYGMSFGRGPLSNPFIAIG-DFLLDPPVGDALMGQIFAAF-------------------LFQ 121
            :|..||           |.|:| :|||      |..|..:|..                   :.|
Mouse    81 FLQRYG-----------FSAVGFNFLL------AAFGIQWALLMQGWFHYFEEGHIVLSVENIIQ 128

  Fly   122 LSFATTATTIVSGAMAERCNFKAYCLFSFLNTAVYCIPAGWVWGEHGFLNKLGAVDIAGSGPVHL 186
            ..|...::.:..||:..:.:.....:.:|....::.:      .|...||.:.|.|..||..:|.
Mouse   129 ADFCVASSCVAFGAVLGKVSPMQLLIMTFFQVTLFTV------NEFILLNLIEAKDAGGSMTIHT 187

  Fly   187 IGGASAFASAAM--------LGPRLGRYSEGYDPLPLGNPVNACMGLFVLWWGWLAFNSGSTYGV 243
            .|   |:....:        |.....|.|..|.     :.:.|.:|...||..|.:|||.|::..
Mouse   188 FG---AYFGLTVTWILYRKNLDQSKQRQSSVYH-----SDLFAMIGTLFLWIYWPSFNSASSFHG 244

  Fly   244 SGAKWQYAARAAVMTMMGSFGGGFTS-SIYSFWRHGGGMDIMDLINGVLGSLVSI-TAGCFLYRA 306
            ....     |||:.|.:.......|: ::.|.....|.:|::.:.|..|...|.: ||...:...
Mouse   245 DAQH-----RAALNTYLSLAASVLTTVTVSSIVHKKGKLDMVHIQNATLAGGVGVGTAAEMMLTP 304

  Fly   307 WEALVIGAIGSLFCVLAMP-----LFDRMGVDDPVGASAVHGVCGIWGVIAVGLFADNPIPLDTT 366
            :.||::|....:|..|...     |..|..:.|..|...:||:.||.|.|...:.|....|  ..
Mouse   305 YGALIVGFFCGIFSTLGFAYLTPFLESRHRIQDTCGIHNLHGIPGIIGGIVGAVTAAYSSP--DV 367

  Fly   367 NGRSGLFKGGGW 378
            .|..|:....|:
Mouse   368 YGEPGIVHSFGF 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Amt	NP_001097800.1	Ammonium_transp	30..428	CDD:275788	85/395 (22%)
Rhcg	NP_062773.2	Ammonium_transp	61..436	CDD:275788	77/357 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D910733at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16229
SonicParanoid	1	1.000	-	-		X200
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950