DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Amt and RHCG

DIOPT Version :9

Sequence 1:	NP_001097800.1	Gene:	Amt / 41841	FlyBaseID:	FBgn0038309	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_001307970.1	Gene:	RHCG / 51458	HGNCID:	18140	Length:	479	Species:	Homo sapiens

Alignment Length:	448	Identity:	102/448 - (22%)
Similarity:	162/448 - (36%)	Gaps:	102/448 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RNHSN---------YVIPGLYDLSVEDTNWVLTSSFIIFTMQTGFGMLESGCVSIKNEVNIMMKN 65
            |.|.|         |..|...|:.|           ::|   .|||.|          :..:.:.
Human    44 RTHKNLSDMENEFYYRYPSFQDVHV-----------MVF---VGFGFL----------MTFLQRY 84

  Fly    66 VIDIVLGGFTYWLFGYGMSFG---RG---PLSNPFIAIGDFLLDPPVGDALMGQIFAAFLFQLSF 124
            ....|  ||.:.|..:|:.:.   :|   .|.:.:|.:|                 ...|....|
Human    85 GFSAV--GFNFLLAAFGIQWALLMQGWFHFLQDRYIVVG-----------------VENLINADF 130

  Fly   125 ATTATTIVSGAMAERCNFKAYCLFSFLNTAVYCIPAGWVWGEHGFLNKLGAVDIAGSGPVHLIGG 189
            ...:..:..||:..:.:.....:.:|....::.:      .|...||.|...|..||..:|..|.
Human   131 CVASVCVAFGAVLGKVSPIQLLIMTFFQVTLFAV------NEFILLNLLKVKDAGGSMTIHTFGA 189

  Fly   190 ASAFASAAMLGPRLGRYSEGYDPLPLGNPVNACMGLFVLWWGWLAFNSGSTY-GVSGAKWQYAAR 253
            ........:|..|....|:........:.:.|.:|...||..|.:|||..:| |.|    |:  |
Human   190 YFGLTVTRILYRRNLEQSKERQNSVYQSDLFAMIGTLFLWMYWPSFNSAISYHGDS----QH--R 248

  Fly   254 AAVMTMMGSFGGGFTS-SIYSFWRHGGGMDIMDLINGVLGSLVSI-TAGCFLYRAWEALVI---- 312
            ||:.|.........|| :|.|.....|.:|::.:.|..|...|:: ||...:...:.||:|
Human   249 AAINTYCSLAACVLTSVAISSALHKKGKLDMVHIQNATLAGGVAVGTAAEMMLMPYGALIIGFVC 313

  Fly   313 GAIGSLFCVLAMPLFD-RMGVDDPVGASAVHGVCGIWGVIAVGLFADNPIPLDTTNGRSGL---- 372
            |.|.:|..|...|..: |:.:.|..|.:.:||:.||.|.| ||........|: ..|:.||
Human   314 GIISTLGFVYLTPFLESRLHIQDTCGINNLHGIPGIIGGI-VGAVTAASASLE-VYGKEGLVHSF 376

  Fly   373 -FKG--GGW--------YLLGIQTLSALCLACWGVCSTFLLLYVINKIIPIRMDPHEE 419
             |:|  |.|        .:.|:  |..|.:|..|.....|:|.     :|....|.:|
Human   377 DFQGFNGDWTARTQGKFQIYGL--LVTLAMALMGGIIVGLILR-----LPFWGQPSDE 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Amt	NP_001097800.1	Ammonium_transp	30..428	CDD:275788	95/419 (23%)
RHCG	NP_001307970.1	Ammonium_transp	60..435	CDD:322161	98/432 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D910733at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X200
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920