DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Amt and amt2

DIOPT Version :9

Sequence 1:	NP_001097800.1	Gene:	Amt / 41841	FlyBaseID:	FBgn0038309	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_593462.1	Gene:	amt2 / 2543501	PomBaseID:	SPAC664.14	Length:	512	Species:	Schizosaccharomyces pombe

Alignment Length:	438	Identity:	128/438 - (29%)
Similarity:	197/438 - (44%)	Gaps:	48/438 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 YDLSVEDTNWVLTSSFIIFTMQTGFGMLESGCVSIKNEVNIMMKNVIDIVLGGFTYWLFGYGMSF 85
            ||..  :|:|:|..:.:...|..|.....||....||.:.::|.:::.:.:..|.::.:||.::|
pombe    42 YDYG--NTSWILACTPLCLIMVPGVAFFYSGLARRKNTLALIMLSMLGLCVSFFQWYFWGYSLAF 104

  Fly    86 GR----GPLSN----PFI-AIGDFLLDPPVGDALMGQIFAAFLFQLSFATTATTIVSGAMAERCN 141
            .:    |.:.|    .|| .:.|:   .|..:.:...:||.  ||..||.....:.:||.|||..
pombe   105 SQTGTSGYIGNLRHFAFIRTLADY---SPGSNNIPELVFAN--FQGMFAAITVALFTGAAAERGR 164

  Fly   142 FKAYCLFSFL-NTAVYCIPAGWVWGEHGFLNKLGAVDIAGSGPVHLIGGASAFASAAMLGPRLGR 205
            .....:.:|: .|.|||..|.|:|..:|:..|.|..|.||.|||.:..|.:|.|....||.|...
pombe   165 IGPMLIITFVWLTVVYCPIACWIWNPNGWAFKFGVYDFAGGGPVEVGSGFAALAYTVCLGRRSKF 229

  Fly   206 YSEGYDPLPLGNPVNACMGLFVLWWGWLAFNSGSTYGVSGAKWQYAARAAVMTMMGSFGGGFTSS 270
            ..|.:.|   .:.:|..:|..:||:|||.||.||.|| |..:   ||.|...|.:.....|....
pombe   230 VEEQFRP---HSVLNVVLGTSLLWFGWLGFNGGSAYG-SNLR---AAMAITNTNLAGAVAGLVWV 287

  Fly   271 IYSFWRHGGGMDIMDLINGVLGSLVSITAGCFLYRAWEALVIGAIGSLFCVLAMPLFDRMGVDDP 335
            ||.:.........:...:||:..||:.|..........:|.||||..|.|..|:.|...|.:||.
pombe   288 IYDYIFRTRKWSTIGFCSGVVAGLVAATPCAGFVSPHASLAIGAITGLCCNWAIKLKSHMRIDDA 352

  Fly   336 VGASAVHGVCGIWGVIAVGLFADNPIPLDTTNGRSGLFKG-----GGWY-----LLGIQTLSALC 390
            :...|:|||.|..|....||||     :|......|::.|     |||:     .||:|......
pombe   353 MDIFAIHGVAGFVGTFLNGLFA-----VDYIAAMDGIYVGENKIRGGWFDHHWRQLGLQMAYICA 412

  Fly   391 LACWGVCSTFLLLYVINKI--IPIRMDPHEELLGADLTEHRIRHSQIG 436
            :..:....||::|::.:||  :.:|:.|..|.:|.|.       .|||
pombe   413 VGAYDFVVTFIILFITDKIPYLQLRVSPDAEEIGVDA-------DQIG 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Amt	NP_001097800.1	Ammonium_transp	30..428	CDD:275788	122/419 (29%)
amt2	NP_593462.1	AmtB	42..464	CDD:223083	128/438 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	175	1.000	Domainoid score	I855
eggNOG	1	0.900	-	-		E1_COG0004
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	176	1.000	Inparanoid score	I1151
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001736
OrthoInspector	1	1.000	-	-		otm47208
orthoMCL	1	0.900	-	-		OOG6_100186
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16229
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.750