DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Amt and amt1

DIOPT Version :9

Sequence 1:	NP_001097800.1	Gene:	Amt / 41841	FlyBaseID:	FBgn0038309	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_588424.1	Gene:	amt1 / 2539332	PomBaseID:	SPCPB1C11.01	Length:	497	Species:	Schizosaccharomyces pombe

Alignment Length:	481	Identity:	140/481 - (29%)
Similarity:	227/481 - (47%)	Gaps:	47/481 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 DTNWVLTSSFIIFTMQTGFGMLESGCVSIKNEVNIMMKNVIDIVLGGFTYWLFGYGMSFGRGPLS 91
            |..|:|||:.::|.|..|.|...||....::.::::..:::.:.:..|.::.:||.::|...  .
pombe    32 DVAWILTSTALVFIMIPGVGFFYSGLARRRSAISMLFLSMMSVAIVAFQWFFWGYSLTFSHE--G 94

  Fly    92 NPFI-AIGDFLLDPPVGDALMGQ------IFAAFLFQLSFATTATTIVSGAMAERCNFKAYCLFS 149
            .|:| ::.:|.|...:|....|.      :|.  :||..||.....:..||.|:|.......:|.
pombe    95 GPYIGSLANFGLRQTLGRPSSGASSVPDILFC--VFQGMFAAITPALAIGAAADRGRMFPCMVFM 157

  Fly   150 FLNTAVYCIP-AGWVWGEHGFLNKLGAVDIAGSGPVHLIGGASAFASAAMLGPRLGRYSEGYDPL 213
            ||.|::...| |.|.|..:|:|||||:.|.||..|||:..|.:|.|.:.::|.|....:..|.|
pombe   158 FLWTSIVYDPIAFWTWNPNGWLNKLGSYDFAGGSPVHISSGMAALAYSIVIGKRCDHGTTKYRP- 221

  Fly   214 PLGNPVNACMGLFVLWWGWLAFNSGSTYGVSGAKWQYAARAAVMTMMGSFGGGFTSSIYSFW--R 276
              .|..:..:|...||:||..||.||    |.|.......|.|:|.:.:..||....:..|.  |
pombe   222 --HNVPHVVLGTVFLWFGWFGFNGGS----SAAANMRGVMAVVVTHLAASVGGIVWCVIDFAKNR 280

  Fly   277 HGGGMDIMDLINGVLGSLVSITAGCFLYRAWEALVIGAIGSLFCVLAMPLFDRMGVDDPVGASAV 341
            |   ..::....|.:..||:||.|......|.|:||||:|::||..|..|...:.|||.:...|.
pombe   281 H---WSVVGFCEGAVAGLVAITPGSGFVPPWAAVVIGALGAVFCYAATYLKKIIRVDDALDIFAE 342

  Fly   342 HGVCGIWGVIAVGLFADNPIPLDTTNGRSGLFKGGGW----YL-LGIQTLSALCLACWGVCSTFL 401
            |||.|:.|.|...|||.:.|  :..:| ||....|||    |: ||.|....:..|.:....:..
pombe   343 HGVGGMVGNILTALFAADYI--EALDG-SGTAYTGGWITHHYIQLGYQLADTVSCAAYSFAVSCA 404

  Fly   402 LLYVINKI--IPIRMDPHEELLGADLTEHRIRHSQIGLSRAISALAPIKVDLKDIAGIQ----PI 460
            ||:|:|.|  :.:|:...:|:||.|..|  :..|......:.....||..     :|:|    .:
pombe   405 LLFVMNYIPGLSLRVSREDEVLGLDKIE--LGESAYYYKDSTDEPPPITT-----SGVQYTSPTV 462

  Fly   461 GINPGHERSIDQLRAAEDKLQQWQSY 486
            ..:..:|:  :|...|:::.|:.:.|
pombe   463 SDSASNEK--EQEHRAQNEAQKEEEY 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Amt	NP_001097800.1	Ammonium_transp	30..428	CDD:275788	128/414 (31%)
amt1	NP_588424.1	AmtB	28..445	CDD:223083	131/431 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	175	1.000	Domainoid score	I855
eggNOG	1	0.900	-	-		E1_COG0004
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	176	1.000	Inparanoid score	I1151
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001736
OrthoInspector	1	1.000	-	-		otm47208
orthoMCL	1	0.900	-	-		OOG6_100186
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16229
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.750