Protein Alignment Hsc70-4 and hscA

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_417021.1
• Gene: hscA / 944885
• ECOCYCID: EG12130
• Length: 616
• Species: Escherichia coli
• Alignment Length: 555
• Identity: 222/555 - (40%)
• Similarity: 320/555 - (57%)
• Gaps: 34/555 - (6%)

  Fly     1 MSKAP-----AVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60
            :|.||     |.|||||||.|.|...:.|:.|.:|:.:|....||.|.:......:|..|:...|
E. coli    11 LSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETLADHEGRHLLPSVVHYQQQGHSVGYDARTNAA 75

  Fly    61 MNPTQTIFDAKRLIGRKFDDAAVQSDMKHWPFEV-VSADGKPKIEVTYKDEKKTFFPEEISSMVL 124
            ::...||...|||:||...|  :|....|.|::. .|.:|.|.||..    .....|..:|:.:|
E. coli    76 LDTANTISSVKRLMGRSLAD--IQQRYPHLPYQFQASENGLPMIETA----AGLLNPVRVSADIL 134

  Fly   125 TKMKETAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKA 189
            ..:...|...|...:...||||||||:|:|||.||||..:|||:|||::|||||||||||||.
E. coli   135 KALAARATEALAGELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDS-- 197

  Fly   190 VGERNVL-IFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDL 253
             |:..|: ::||||||||:|||.:..|:|||.:|.||:.|||:|||:.|..:..::.....:.|
E. coli   198 -GQEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIPDRSD- 260

  Fly   254 TTNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVE 318
               .|..|.|..|...||..||.:...::.:.. ::|     .|:|.:|.||.|.|.:.|:....
E. coli   261 ---NRVQRELLDAAIAAKIALSDADSVTVNVAG-WQG-----EISREQFNELIAPLVKRTLLACR 316

  Fly   319 KALRDAKLDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGD 383
            :||:||.::...:.::|:||||||:|.|:..:.:.| |:....||:||:.||.|||:||.||.|:
E. coli   317 RALKDAGVEADEVLEVVMVGGSTRVPLVRERVGEFF-GRPPLTSIDPDKVVAIGAAIQADILVGN 380

  Fly   384 KSQEVQDLLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERA 448
            |..  .::|||||.|||||:||.||::..:|.||||||..:.|.|||:.|.|..:.|.|.:|||.
E. coli   381 KPD--SEMLLLDVIPLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERE 443

  Fly   449 MTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKE 513
            :.:|...|.:|.|.|||..|.|...|.|||.:||:|:|:|||:|:||..|..|.:....| |:..
E. coli   444 LVQDCRSLARFALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYG-LTDS 507

  Fly   514 DIERMVNEAEKYRNEDEKQK----ETIAAKNGLES 544
            :|..|:.::..|..:|.|.:    :.:.|...|||
E. coli   508 EIASMIKDSMSYAEQDVKARMLAEQKVEAARVLES 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	222/555 (40%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	148/376 (39%)
hscA	NP_417021.1	hscA	1..616	CDD:235360	222/555 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19375
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
	3	3.000