Protein Alignment Hsc70-4 and SSZ1

DIOPT Version :10

• Sequence 1: NP_524356.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_011931.2
• Gene: SSZ1 / 856461
• SGDID: S000001106
• Length: 538
• Species: Saccharomyces cerevisiae
• Alignment Length: 548
• Identity: 161/548 - (29%)
• Similarity: 261/548 - (47%)
• Gaps: 66/548 - (12%)

  Fly     4 APAVGIDLGTTYSCVG-VFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTI 67
            :|.:||..|.|.|.:. :.....|::|||..|.|..||.:::...:...|..|..|:..||..||
Yeast     3 SPVIGITFGNTSSSIAYINPKNDVDVIANPDGERAIPSALSYVGEDEYHGGQALQQLIRNPKNTI 67

  Fly    68 FDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEV-----------TYKDEKKTFFPEEISS 121
            .:.:..||..||...|..          .|:|.|.:||           ..|:||.|.  :|:.|
Yeast    68 INFRDFIGLPFDKCDVSK----------CANGAPAVEVDGKVGFVISRGEGKEEKLTV--DEVVS 120

  Fly   122 MVLTKMKETAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLD 186
            ..|.::|..||.|:|..|..||:|||..|::.|:.|.|.:....||.:::.||||:||.:|:...
Yeast   121 RHLNRLKLAAEDYIGSAVKEAVLTVPTNFSEEQKTALKASAAKIGLQIVQFINEPSAALLAHAEQ 185

  Fly   187 KKAVGERNVLIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKK 251
            .....:.||::.|.||...|.:::::.:|||.:.:||.|..|||::.|..||.:|..||::|::.
Yeast   186 FPFEKDVNVVVADFGGIRSDAAVIAVRNGIFTILATAHDLSLGGDNLDTELVEYFASEFQKKYQA 250

  Fly   252 DLTTNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDP 316
            :...|.|:|.:|:......|:|||::|.|:|.||||.:|.|::.||.|.|:|.:...:|......
Yeast   251 NPRKNARSLAKLKANSSITKKTLSNATSATISIDSLADGFDYHASINRMRYELVANKVFAQFSSF 315

  Fly   317 VEKALRDAKLDKSVIHDIVLVGGSTRIPKVQRLLQ-------DLFNGKELNKSINPDEAVAYGAA 374
            |:..:..|:||...|..::|.||.:..||:...|:       ::...:..|.|.||:|..|.|||
Yeast   316 VDSVIAKAELDPLDIDAVLLTGGVSFTPKLTTNLEYTLPESVEILGPQNKNASNNPNELAASGAA 380

  Fly   375 VQAAILHGDKSQEVQDLL--LLDVTP---LSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDN 434
            :||.::....:.|:.:.|  ::..||   ..:|:..|.|....::...|:.|   .|...|....
Yeast   381 LQARLISDYDADELAEALQPVIVNTPHLKKPIGLIGAKGEFHPVLLAETSFP---VQKKLTLKQA 442

  Fly   435 QPGVLIQVYEGE--------RAMTKDNNLLGKFELSGIPPAPRGVPQ------------------ 473
            :...||.||||:        ..:.|:.|.....|.......|..|.:
Yeast   443 KGDFLIGVYEGDHHIEEKTLEPIPKEENAEEDDESEWSDDEPEVVREKLYTLGTKLMELGIKNAN 507

  Fly   474 -IEVTFDIDANGILNVTALERSTNKENK 500
             :|:.|:|:.:|.|.|||.:..|....|
Yeast   508 GVEIIFNINKDGALRVTARDLKTGNAVK 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_524356.1	PTZ00009	1..612	CDD:240227	161/548 (29%)
SSZ1	NP_011931.2	ASKHA_NBD_HSP70_ScSsz1p-like	4..386	CDD:466830	129/393 (33%)