Protein Alignment Hsc70-4 and SSB2

DIOPT Version :10

• Sequence 1: NP_524356.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_014190.1
• Gene: SSB2 / 855512
• SGDID: S000005153
• Length: 613
• Species: Saccharomyces cerevisiae
• Alignment Length: 606
• Identity: 367/606 - (60%)
• Similarity: 460/606 - (75%)
• Gaps: 8/606 - (1%)

  Fly     6 AVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDA 70
            |:|||||||||||..:: ..||||||:||||.|||:||||..|||||||||||.|:||..|:|||
Yeast     9 AIGIDLGTTYSCVATYE-SSVEIIANEQGNRVTPSFVAFTPQERLIGDAAKNQAALNPRNTVFDA 72

  Fly    71 KRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAEAYL 135
            ||||||:|||.:||.|||.|||:|:..||.|.|||.|.:|.|||.|:|||:||||||||.|||.:
Yeast    73 KRLIGRRFDDESVQKDMKTWPFKVIDVDGNPVIEVQYLEETKTFSPQEISAMVLTKMKEIAEAKI 137

  Fly   136 GKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDK-KAVGERNVLIFD 199
            ||.|..|||||||||||:|||||||||.|:||||||||||||||||||||.. |:..||:|||||
Yeast   138 GKKVEKAVITVPAYFNDAQRQATKDAGAISGLNVLRIINEPTAAAIAYGLGAGKSEKERHVLIFD 202

  Fly   200 LGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRRLR 264
            |||||||||:|.|..|::.||||:|:|||||:|||..|:.||..|||:|...|::.:.|||||||
Yeast   203 LGGGTFDVSLLHIAGGVYTVKSTSGNTHLGGQDFDTNLLEHFKAEFKKKTGLDISDDARALRRLR 267

  Fly   265 TACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAKLDKS 329
            ||.|||||||||.||.::|:||||:|.||.:|:||||||:|||.||:||::|||:.|:|||:.||
Yeast   268 TAAERAKRTLSSVTQTTVEVDSLFDGEDFESSLTRARFEDLNAALFKSTLEPVEQVLKDAKISKS 332

  Fly   330 VIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDK-SQEVQDLLL 393
            .|.::|||||||||||||:||.|.|:||:|.||||||||||||||||.|||.|.. |.|.:||||
Yeast   333 QIDEVVLVGGSTRIPKVQKLLSDFFDGKQLEKSINPDEAVAYGAAVQGAILTGQSTSDETKDLLL 397

  Fly   394 LDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGK 458
            |||.|||||:...|.:..:::.||||:||.:.:||||.||||..|...||:|||...|:|.|||:
Yeast   398 LDVAPLSLGVGMQGDIFGIVVPRNTTVPTIKRRTFTTVSDNQTTVQFPVYQGERVNCKENTLLGE 462

  Fly   459 FELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVNEAE 523
            |:|..||..|.|.|.:|..|::||||||.|||:|:||.|.:.|||:|..||||.|:||:|||:||
Yeast   463 FDLKNIPMMPAGEPVLEAIFEVDANGILKVTAVEKSTGKSSNITISNAVGRLSSEEIEKMVNQAE 527

  Fly   524 KYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQLAD 588
            :::..||...:...|:..||||..:::.|:.:..|.:|:....::.|....::.   |.|.|:.|
Yeast   528 EFKAADEAFAKKHEARQRLESYVASIEQTVTDPVLSSKLKRGSKSKIEAALSDA---LAALQIED 589

  Fly   589 KEEYEHRQKELEGVCNPIITK 609
            ....|.|:.|: |: ..::||
Yeast   590 PSADELRKAEV-GL-KRVVTK 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_524356.1	PTZ00009	1..612	CDD:240227	367/606 (61%)
SSB2	NP_014190.1	PTZ00009	6..575	CDD:240227	356/566 (63%)