Protein Alignment Hsc70-4 and KAR2

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_012500.3
• Gene: KAR2 / 853418
• SGDID: S000003571
• Length: 682
• Species: Saccharomyces cerevisiae
• Alignment Length: 609
• Identity: 379/609 - (62%)
• Similarity: 482/609 - (79%)
• Gaps: 5/609 - (0%)

  Fly     7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDAK 71
            :|||||||||||.|.::||.||:||:||||.|||||||||.|||||||||||||.||..||||.|
Yeast    53 IGIDLGTTYSCVAVMKNGKTEILANEQGNRITPSYVAFTDDERLIGDAAKNQVAANPQNTIFDIK 117

  Fly    72 RLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAEAYLG 136
            ||||.|::|.:||.|:||.||.||:.||||.:||:.|.|||.|.|||||.|:|.|||:.||.|||
Yeast   118 RLIGLKYNDRSVQKDIKHLPFNVVNKDGKPAVEVSVKGEKKVFTPEEISGMILGKMKQIAEDYLG 182

  Fly   137 KTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNVLIFDLG 201
            ..||:||:||||||||:|||||||||||||||||||:||||||||||||| |:..|..::::|||
Yeast   183 TKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVLRIVNEPTAAAIAYGLD-KSDKEHQIIVYDLG 246

  Fly   202 GGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRRLRTA 266
            |||||||:|||::|:|||::|:|||||||||||.::|...::.||:||..|::.|.:||.:|:..
Yeast   247 GGTFDVSLLSIENGVFEVQATSGDTHLGGEDFDYKIVRQLIKAFKKKHGIDVSDNNKALAKLKRE 311

  Fly   267 CERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAKLDKSVI 331
            .|:|||.|||.....|||||..:|.|...::|||:|||||.|||:.|:.||||.|:|:.|:|..:
Yeast   312 AEKAKRALSSQMSTRIEIDSFVDGIDLSETLTRAKFEELNLDLFKKTLKPVEKVLQDSGLEKKDV 376

  Fly   332 HDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQDLLLLDV 396
            .|||||||||||||||:||:..|:||:.:|.|||||||||||||||.:|.|::.  |:|::||||
Yeast   377 DDIVLVGGSTRIPKVQQLLESYFDGKKASKGINPDEAVAYGAAVQAGVLSGEEG--VEDIVLLDV 439

  Fly   397 TPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFEL 461
            ..|:|||||.||||:.||||||.||||::|.|:|..||||.|:|:||||||||:|||||||||||
Yeast   440 NALTLGIETTGGVMTPLIKRNTAIPTKKSQIFSTAVDNQPTVMIKVYEGERAMSKDNNLLGKFEL 504

  Fly   462 SGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVNEAEKYR 526
            :||||||||||||||||.:||||||.|:|.::.|.|...||||||||||::|:|:|||.||||:.
Yeast   505 TGIPPAPRGVPQIEVTFALDANGILKVSATDKGTGKSESITITNDKGRLTQEEIDRMVEEAEKFA 569

  Fly   527 NEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDAN-QLADKE 590
            :||...|..:.::|.||:|..::|..::.| |..|:.:.|:.|:||..|:.::|||.| :.|..|
Yeast   570 SEDASIKAKVESRNKLENYAHSLKNQVNGD-LGEKLEEEDKETLLDAANDVLEWLDDNFETAIAE 633

  Fly   591 EYEHRQKELEGVCNPIITKLYQGA 614
            :::.:.:.|..|..||.:|||.||
Yeast   634 DFDEKFESLSKVAYPITSKLYGGA 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	376/605 (62%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	247/373 (66%)
KAR2	NP_012500.3	HSP70	52..654	CDD:394970	375/604 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.720