Protein Alignment Hsc70-4 and SSB1

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_010052.1
• Gene: SSB1 / 851369
• SGDID: S000002388
• Length: 613
• Species: Saccharomyces cerevisiae
• Alignment Length: 606
• Identity: 366/606 - (60%)
• Similarity: 460/606 - (75%)
• Gaps: 8/606 - (1%)

  Fly     6 AVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDA 70
            |:|||||||||||..:: ..||||||:||||.|||:||||..|||||||||||.|:||..|:|||
Yeast     9 AIGIDLGTTYSCVATYE-SSVEIIANEQGNRVTPSFVAFTPEERLIGDAAKNQAALNPRNTVFDA 72

  Fly    71 KRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAEAYL 135
            ||||||:|||.:||.|||.|||:|:..||.|.|||.|.:|.|||.|:|||:||||||||.|||.:
Yeast    73 KRLIGRRFDDESVQKDMKTWPFKVIDVDGNPVIEVQYLEETKTFSPQEISAMVLTKMKEIAEAKI 137

  Fly   136 GKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDK-KAVGERNVLIFD 199
            ||.|..|||||||||||:|||||||||.|:||||||||||||||||||||.. |:..||:|||||
Yeast   138 GKKVEKAVITVPAYFNDAQRQATKDAGAISGLNVLRIINEPTAAAIAYGLGAGKSEKERHVLIFD 202

  Fly   200 LGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRRLR 264
            |||||||||:|.|..|::.||||:|:|||||:|||..|:.||..|||:|...|::.:.|||||||
Yeast   203 LGGGTFDVSLLHIAGGVYTVKSTSGNTHLGGQDFDTNLLEHFKAEFKKKTGLDISDDARALRRLR 267

  Fly   265 TACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAKLDKS 329
            ||.|||||||||.||.::|:||||:|.||.:|:||||||:|||.||:||::|||:.|:|||:.||
Yeast   268 TAAERAKRTLSSVTQTTVEVDSLFDGEDFESSLTRARFEDLNAALFKSTLEPVEQVLKDAKISKS 332

  Fly   330 VIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDK-SQEVQDLLL 393
            .|.::|||||||||||||:||.|.|:||:|.||||||||||||||||.|||.|.. |.|.:||||
Yeast   333 QIDEVVLVGGSTRIPKVQKLLSDFFDGKQLEKSINPDEAVAYGAAVQGAILTGQSTSDETKDLLL 397

  Fly   394 LDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGK 458
            |||.|||||:...|.:..:::.||||:||.:.:||||.:|||..|...||:|||...|:|.|||:
Yeast   398 LDVAPLSLGVGMQGDMFGIVVPRNTTVPTIKRRTFTTCADNQTTVQFPVYQGERVNCKENTLLGE 462

  Fly   459 FELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVNEAE 523
            |:|..||..|.|.|.:|..|::||||||.|||:|:||.|.:.|||:|..||||.|:||:|||:||
Yeast   463 FDLKNIPMMPAGEPVLEAIFEVDANGILKVTAVEKSTGKSSNITISNAVGRLSSEEIEKMVNQAE 527

  Fly   524 KYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQLAD 588
            :::..||...:...|:..||||..:::.|:.:..|.:|:....::.|....::.   |.|.|:.|
Yeast   528 EFKAADEAFAKKHEARQRLESYVASIEQTVTDPVLSSKLKRGSKSKIEAALSDA---LAALQIED 589

  Fly   589 KEEYEHRQKELEGVCNPIITK 609
            ....|.|:.|: |: ..::||
Yeast   590 PSADELRKAEV-GL-KRVVTK 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	366/606 (60%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	266/375 (71%)
SSB1	NP_010052.1	PTZ00009	6..575	CDD:240227	355/566 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341915
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.600