Protein Alignment Hsc70-4 and SSA1

DIOPT Version :10

• Sequence 1: NP_524356.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_009396.2
• Gene: SSA1 / 851259
• SGDID: S000000004
• Length: 642
• Species: Saccharomyces cerevisiae
• Alignment Length: 651
• Identity: 483/651 - (74%)
• Similarity: 555/651 - (85%)
• Gaps: 9/651 - (1%)

  Fly     1 MSKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQ 65
            |||  |||||||||||||..|.:.:|:|||||||||||||:|||||||||||||||||.||||:.
Yeast     1 MSK--AVGIDLGTTYSCVAHFANDRVDIIANDQGNRTTPSFVAFTDTERLIGDAAKNQAAMNPSN 63

  Fly    66 TIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKET 130
            |:|||||||||.|:|..||:||||:||:::..||||:|:|.:|.|.|.|.||:||||||.|||||
Yeast    64 TVFDAKRLIGRNFNDPEVQADMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKET 128

  Fly   131 AEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNV 195
            ||:|||..|.:||:||||||||||||||||||||||||||||||||||||||||||||. .|.:|
Yeast   129 AESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKG-KEEHV 192

  Fly   196 LIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRAL 260
            |||||||||||||:|||:|||||||:|||||||||||||||||.||:||||||:||||:||:|||
Yeast   193 LIFDLGGGTFDVSLLSIEDGIFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRAL 257

  Fly   261 RRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAK 325
            |||||||||||||||||.|.|:||||||||.||||||||||||||.|||||||:|||||.|||||
Yeast   258 RRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAK 322

  Fly   326 LDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQD 390
            ||||.:.:||||||||||||||:|:.|.|||||.|:|||||||||||||||||||.||:|.:.||
Yeast   323 LDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQD 387

  Fly   391 LLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNL 455
            ||||||.|||||||||||||:.||.||:|||||:::.|:||:||||||||||:|||||.||||||
Yeast   388 LLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEIFSTYADNQPGVLIQVFEGERAKTKDNNL 452

  Fly   456 LGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVN 520
            ||||||||||||||||||||||||:|:||||||:|:|:.|.|.||||||||||||||||||:||.
Yeast   453 LGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVA 517

  Fly   521 EAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQ 585
            ||||::.||||:.:.||:||.|||..:::|.|:.|..  .|:..:|:.|:..|..|||.|||:|.
Yeast   518 EAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDTVTKKAEETISWLDSNT 580

  Fly   586 LADKEEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGGPGGMPGAAGAAGAAGAGGAGPTIEEV 650
            .|.|||::.:.|||:.:.|||::||||..|.|.|...|.|||.||.|..|..|    .|||:|||
Yeast   581 TASKEEFDDKLKELQDIANPIMSKLYQAGGAPGGAAGGAPGGFPGGAPPAPEA----EGPTVEEV 641

  Fly   651 D 651
            |
Yeast   642 D 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_524356.1	PTZ00009	1..612	CDD:240227	462/610 (76%)
SSA1	NP_009396.2	PTZ00009	4..642	CDD:240227	478/644 (74%)