Protein Alignment Hsc70-4 and SSQ1

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_013473.1
• Gene: SSQ1 / 851084
• SGDID: S000004361
• Length: 657
• Species: Saccharomyces cerevisiae
• Alignment Length: 649
• Identity: 275/649 - (42%)
• Similarity: 397/649 - (61%)
• Gaps: 72/649 - (11%)

  Fly     7 VGIDLGTTYSCVGVFQHG----KVEIIANDQGNRTTPSYVAF---------TDTERLIGDAAKNQ 58
            :|||||||.|.|...:..    ...||.||:|.|||||.|||         ...:.|:|.|||.|
Yeast    31 IGIDLGTTNSAVAYIRDSNDKKSATIIENDEGQRTTPSIVAFDVKSSPQNKDQMKTLVGMAAKRQ 95

  Fly    59 VAMNPTQTIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFF--PEEISS 121
            .|:|...|.|..||||||.|:|..||.||...|:::|..:...:   .|........  |.:|:|
Yeast    96 NAINSENTFFATKRLIGRAFNDKEVQRDMAVMPYKIVKCESNGQ---AYLSTSNGLIQSPSQIAS 157

  Fly   122 MVLTKMKETAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLD 186
            ::|..:|:|:|.|||:.|..|||||||||||||||||||||.:|||||||:||||||||:::|:|
Yeast   158 ILLKYLKQTSEEYLGEKVNLAVITVPAYFNDSQRQATKDAGKLAGLNVLRVINEPTAAALSFGID 222

  Fly   187 KKAVGERN---VLIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRK 248
            .|    ||   :.::||||||||:|||.|:||:|||::|.||||||||||||.:|.:.:..|..:
Yeast   223 DK----RNNGLIAVYDLGGGTFDISILDIEDGVFEVRATNGDTHLGGEDFDNVIVNYIIDTFIHE 283

  Fly   249 H----KKDLTTNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADL 309
            :    ::::|.|:..::||:...||||..||...:..||:..:::.......:|....:.:...|
Yeast   284 NPEITREEITKNRETMQRLKDVSERAKIDLSHVKKTFIELPFVYKSKHLRVPMTEEELDNMTLSL 348

  Fly   310 FRSTMDPVEKALRDAKLDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAA 374
            ...|:.||::||:||.::...|.:::||||.||:||::.:::||| ||..|.|:||||.||.|||
Yeast   349 INRTIPPVKQALKDADIEPEDIDEVILVGGMTRMPKIRSVVKDLF-GKSPNSSVNPDETVALGAA 412

  Fly   375 VQAAILHGDKSQEVQDLLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVL 439
            :|..||.|    |::::||||||||:|||||.||..|.||.||||:|.|:|:.|:|..|.|.||.
Yeast   413 IQGGILSG----EIKNVLLLDVTPLTLGIETFGGAFSPLIPRNTTVPVKKTEIFSTGVDGQAGVD 473

  Fly   440 IQVYEGERAMTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITIT 504
            |:|::|||.:.::|.|:|..:|:||.|.|:|:|||.|||||||:||:||:|.|:|:.|:..||:.
Yeast   474 IKVFQGERGLVRNNKLIGDLKLTGITPLPKGIPQIYVTFDIDADGIINVSAAEKSSGKQQSITVI 538

  Fly   505 NDKGRLSKEDIERMVNEAEKYRNEDE--KQKETIAAKNGLESYCFNMKATLDEDNL-----KTKI 562
            .:.| ||:|:|.:::.||...|.:|.  :|:..:.:|..:        ...|.:||     |...
Yeast   539 PNSG-LSEEEIAKLIEEANANRAQDNLIRQRLELISKADI--------MISDTENLFKRYEKLIS 594

  Fly   563 SDSDRTTILD------------KCNETIKWLDANQLADKEEYEHRQKELEGVCNPIITKLYQGA 614
            |:.:.:.|::            |.||....:|.|.:....:      .|:|..    .||:|.|
Yeast   595 SEKEYSNIVEDIKALRQAIKNFKANENDMSIDVNGIKKATD------ALQGRA----LKLFQSA 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	273/645 (42%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	179/395 (45%)
SSQ1	NP_013473.1	dnaK	29..656	CDD:234715	275/649 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810