DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hsc70-4 and BIP2

DIOPT Version :9

Sequence 1:	NP_001262586.1	Gene:	Hsc70-4 / 41840	FlyBaseID:	FBgn0266599	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	NP_001331824.1	Gene:	BIP2 / 834207	AraportID:	AT5G42020	Length:	673	Species:	Arabidopsis thaliana

Alignment Length:	645	Identity:	409/645 - (63%)
Similarity:	504/645 - (78%)	Gaps:	23/645 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDAK 71
            :|||||||||||||:::|.|||||||||||.|||:|.|||:|||||:|||||.|:||.:|:||.|
plant    43 IGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVGFTDSERLIGEAAKNQAAVNPERTVFDVK 107

  Fly    72 RLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKD-EKKTFFPEEISSMVLTKMKETAEAYL 135
            |||||||:|..||.|.|..|:::|:.||||.|:|..|| |.|.|.|||||:|:||||||||||||
plant   108 RLIGRKFEDKEVQKDRKLVPYQIVNKDGKPYIQVKIKDGETKVFSPEEISAMILTKMKETAEAYL 172

  Fly   136 GKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNVLIFDL 200
            ||.:.:||:||||||||:|||||||||.||||||.||||||||||||||||||. ||:|:|:|||
plant   173 GKKIKDAVVTVPAYFNDAQRQATKDAGVIAGLNVARIINEPTAAAIAYGLDKKG-GEKNILVFDL 236

  Fly   201 GGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRRLRT 265
            ||||||||:|:||:|:|||.||.|||||||||||:|::.:|::..|:||:||::.:.:||.:||.
plant   237 GGGTFDVSVLTIDNGVFEVLSTNGDTHLGGEDFDHRIMEYFIKLIKKKHQKDISKDNKALGKLRR 301

  Fly   266 ACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAKLDKSV 330
            .||||||.|||..|..:||:|||:|.|....:|||||||||.||||.||.||:||:.||.|.||.
plant   302 ECERAKRALSSQHQVRVEIESLFDGVDLSEPLTRARFEELNNDLFRKTMGPVKKAMDDAGLQKSQ 366

  Fly   331 IHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQDLLLLD 395
            |.:||||||||||||||:||:|.|.|||.||.:|||||||||||||..||.|:...|.:|:||||
plant   367 IDEIVLVGGSTRIPKVQQLLKDFFEGKEPNKGVNPDEAVAYGAAVQGGILSGEGGDETKDILLLD 431

  Fly   396 VTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFE 460
            |.||:|||||.||||:.||.|||.||||::|.||||.|.|..|.|||:||||::|||..|||||:
plant   432 VAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTTVSIQVFEGERSLTKDCRLLGKFD 496

  Fly   461 LSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVNEAEKY 525
            |:|:||||||.|||||||::||||||||.|.::::.|..||||||:|||||:|:|:|||.|||::
plant   497 LTGVPPAPRGTPQIEVTFEVDANGILNVKAEDKASGKSEKITITNEKGRLSQEEIDRMVKEAEEF 561

  Fly   526 RNEDEKQKETIAAKNGLESYCFNMKATL-DEDNLKTKISDSDRTTILDKCNETIKWLDANQLADK 589
            ..||:|.||.|.|:|.||:|.:|||..: |:|.|..|:...::..|.....|.::|||.||.::|
plant   562 AEEDKKVKEKIDARNALETYVYNMKNQVSDKDKLADKLEGDEKEKIEAATKEALEWLDENQNSEK 626

  Fly   590 EEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGGPGGMPGAAGAAGAAGAGGAGPTIEE 649
            |||:.:.||:|.|||||||.:||.:|                    ||.||||...|.||
plant   627 EEYDEKLKEVEAVCNPIITAVYQRSG--------------------GAPGAGGESSTEEE 666

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	397/606 (66%)
Hsc70-4	NP_001262586.1	HSPA1-2_6-8-like_NBD	6..381	CDD:212675	262/374 (70%)
BIP2	NP_001331824.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.730