Protein Alignment Hsc70-4 and hspa1b

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001093532.1
• Gene: hspa1b / 798846
• ZFINID: ZDB-GENE-060503-867
• Length: 639
• Species: Danio rerio
• Alignment Length: 653
• Identity: 525/653 - (80%)
• Similarity: 576/653 - (88%)
• Gaps: 16/653 - (2%)

  Fly     1 MSKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQ 65
            |:|..::||||||||||||||||||||||||||||||||||||||||||||||||||||||||..
Zfish     1 MAKGLSIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNN 65

  Fly    66 TIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKET 130
            |||||||||||||||..||||||.|||:|:|.|||||::|.||.|.|||:|||||||||.||:|.
Zfish    66 TIFDAKRLIGRKFDDQVVQSDMKLWPFKVISEDGKPKVQVEYKGENKTFYPEEISSMVLVKMREI 130

  Fly   131 AEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNV 195
            ||||||..|.||||||||||||||||||||||.||||||||||||||||||||||||...|||||
Zfish   131 AEAYLGHRVNNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGRKGERNV 195

  Fly   196 LIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRAL 260
            |||||||||||||||:|:|||||||:|||||||||||||||:|.|||:|||||||||::.||||:
Zfish   196 LIFDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRMVKHFVEEFKRKHKKDISQNKRAV 260

  Fly   261 RRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAK 325
            |||||||||||||||||:||||||||||||.||||||||||||||||:|||.|:|||||||||||
Zfish   261 RRLRTACERAKRTLSSSSQASIEIDSLFEGIDFYTSITRARFEELNAELFRGTLDPVEKALRDAK 325

  Fly   326 LDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQD 390
            :|||.|.|||||||||||||:|:||||.|||::||||||||||||||||||||||.||.|:.|||
Zfish   326 MDKSQIQDIVLVGGSTRIPKIQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDTSENVQD 390

  Fly   391 LLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNL 455
            ||||||.|||||||||||||:.||||||||||||||.|:|||||||||||||:||||||||||||
Zfish   391 LLLLDVAPLSLGIETAGGVMTALIKRNTTIPTKQTQIFSTYSDNQPGVLIQVFEGERAMTKDNNL 455

  Fly   456 LGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVN 520
            ||||:|:||||||||||||||||||||||||||:|.::||.|||||||||||||||||||||||.
Zfish   456 LGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKENKITITNDKGRLSKEDIERMVQ 520

  Fly   521 EAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQ 585
            :||||:.|||.|:|.|||||.||||.|:||.|::::||:.|||:.|:..|:|||.|.:.||:.||
Zfish   521 DAEKYKAEDEVQREKIAAKNALESYAFSMKNTVEDENLRGKISEQDKKKIIDKCTEVVSWLENNQ 585

  Fly   586 LADKEEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGGPGGMPGAAGAAG--AAGAGGAGPTIE 648
            ||:||||||.|||||.||||||::|||| |.||             ||..|  |......|||||
Zfish   586 LAEKEEYEHHQKELESVCNPIISRLYQG-GAPP-------------AGGCGFQAQPESSQGPTIE 636

  Fly   649 EVD 651
            |||
Zfish   637 EVD 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	507/610 (83%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	325/374 (87%)
hspa1b	NP_001093532.1	HSP70	1..639	CDD:331774	523/651 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575287
Domainoid	1	1.000	1033	1.000	Domainoid score	I26
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	1	1.000	-	-		mtm6456
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X148
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.760