Protein Alignment Hsc70-4 and hspa1l

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001072429.1
• Gene: hspa1l / 779883
• XenbaseID: XB-GENE-6045069
• Length: 639
• Species: Xenopus tropicalis
• Alignment Length: 650
• Identity: 533/650 - (82%)
• Similarity: 584/650 - (89%)
• Gaps: 13/650 - (2%)

  Fly     2 SKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQT 66
            ||..|:|||||||||||||||||||||||||||||||||||||||||||||||||||||:||..|
 Frog     3 SKGVAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPHNT 67

  Fly    67 IFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETA 131
            :||||||||||:|:..||||||||||:|:|..||||:.|.||.|.|:|.||||||||||||||||
 Frog    68 VFDAKRLIGRKYDEPVVQSDMKHWPFKVISDGGKPKVTVEYKGEGKSFSPEEISSMVLTKMKETA 132

  Fly   132 EAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNVL 196
            |||||..||||||||||||||||||||||||.||||||||||||||||||||||||...||||:|
 Frog   133 EAYLGYKVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKSGRGERNIL 197

  Fly   197 IFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALR 261
            ||||||||||||||:|||||||||:||||||||||||||.:|.|||:|||||||||::.||||||
 Frog   198 IFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNCMVNHFVEEFKRKHKKDISPNKRALR 262

  Fly   262 RLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAKL 326
            |||||||||||||||||||||||||||||.||||||||||||||.|||||.|::|||||:|||||
 Frog   263 RLRTACERAKRTLSSSTQASIEIDSLFEGIDFYTSITRARFEELCADLFRGTLEPVEKAMRDAKL 327

  Fly   327 DKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQDL 391
            |||.||:||||||||||||||:||||.|||||||||||||||||||||||||||.||||:.||||
 Frog   328 DKSQIHEIVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILMGDKSENVQDL 392

  Fly   392 LLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLL 456
            |||||.|||||:|||||||:||||||||||.||||||||||||||||||||||||||||||||||
 Frog   393 LLLDVAPLSLGLETAGGVMTVLIKRNTTIPIKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLL 457

  Fly   457 GKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVNE 521
            |||:|:||||||||||||||||||||||||||:|:::|:.|:|||||||||||||||:||||:.|
 Frog   458 GKFDLTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSSGKKNKITITNDKGRLSKEEIERMLQE 522

  Fly   522 AEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQL 586
            |:||:.:||:|:|.|||||.||||.||||:|::::|:|.||||||:.:|||||.|.|.||:.|||
 Frog   523 ADKYKADDEQQREKIAAKNSLESYAFNMKSTVEDNNIKDKISDSDKKSILDKCQEVISWLEQNQL 587

  Fly   587 ADKEEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGGPGGMPGAAGAAGAAGAGGAGPTIEEVD 651
            |:||||.|:|||||.:|||||||||||         |.||||||    ||.......||||||||
 Frog   588 AEKEEYTHKQKELEKLCNPIITKLYQG---------GMPGGMPG----AGCTAEPKQGPTIEEVD 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	513/609 (84%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	328/374 (88%)
hspa1l	NP_001072429.1	HSP70	2..639	CDD:331774	531/648 (82%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	1042	1.000	Domainoid score	I28
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	1	1.000	-	-		otm48923
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X148
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.930