Protein Alignment Hsc70-4 and hyou1

DIOPT Version :10

• Sequence 1: NP_524356.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001263614.1
• Gene: hyou1 / 779444
• XenbaseID: XB-GENE-921821
• Length: 985
• Species: Xenopus tropicalis
• Alignment Length: 788
• Identity: 191/788 - (24%)
• Similarity: 336/788 - (42%)
• Gaps: 192/788 - (24%)

  Fly     7 VGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDA 70
            :.:|:|:.:..:.:.:.| .:||:.|.:..|.||..:|..:.|||.||:|......||..|....
 Frog    36 MSVDMGSEWMKIAIVKPGVPMEIVLNKESRRKTPVAIALKENERLFGDSALGMAVKNPKVTFRYF 100

  Fly    71 KRLIGRKFDDAAVQSDMKHWP-FEVVSADGKPKIEVTYK-DEKKTFFPEEISSMVLTKMKETAEA 133
            :.|:|::.|:..|::....:| :::|..:.:.  .|.:| .|:.|:.|||:..|:|...:..||.
 Frog   101 QDLLGKRADNPHVKAFEARFPEYQLVKDEHRE--TVLFKLSEELTYSPEELLGMMLNYSRSLAEE 163

  Fly   134 YLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL----DKKAVGERN 194
            :..:.|.:.||||||:||.::|:|...|..::.|.||::||:.||.|:.||:    |..|..: |
 Frog   164 FAEQPVKDVVITVPAFFNQAERRAVLQAAQLSDLKVLQLINDNTAVALNYGVFRRKDINATAQ-N 227

  Fly   195 VLIFDLGGGTFDVSILSI------DDGI---FEVKSTAGDTHLGGEDFDNRLVTHFVQEF--KRK 248
            ::.:::|..:...:|::.      |.|:   .:::....|..|||.:.|.||..|..:.|  ::|
 Frog   228 IMFYEMGSRSTICTIVTYQSVKTKDSGMQPQLQIRGVGFDRTLGGIEMDLRLRDHLAKLFNEQKK 292

  Fly   249 HKKDLTTNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRST 313
            .|||:..|:||:.:|.....|.|..||::.....:|:.|.:..||...:||...|:|.||||...
 Frog   293 SKKDVRENQRAMSKLLKEANRVKTILSANNDHMAQIEGLMDDIDFKAKVTRQELEDLCADLFNRV 357

  Fly   314 MDPVEKALRDAKLDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAA 378
            ..||:.||..|::....|..::||||:||:||||.||..:...:||.|:||.|||.|.||..|||
 Frog   358 SAPVQHALSSAEMKMEEIDQVILVGGATRVPKVQELLLKVVGKEELGKNINADEAAAMGAVYQAA 422

  Fly   379 ILHGDKSQEVQDLLLLDVTPLSLGIETAGGV------------MSVLIKRNTTIPTKQTQTFTTY 431
            .|  .|:.:|:..::.|.....:.:|....|            ..:|.:|....|.::..||..|
 Frog   423 AL--SKAFKVKPFIVRDAAIFPIQVEFTREVEEEDHSKSLKHNKRILFQRLAPYPQRKVITFNRY 485

  Fly   432 SDNQPGVLIQVYEGERAMTKDNNL-------LGKFELSGIPPA--------PRGVPQIEVTFDID 481
            :||   ....:..|:.:....::|       |...:|:|:..:        .:|   |:..|::|
 Frog   486 TDN---FAFSINYGDLSYLGPDDLKVFGSLNLTTVKLNGVGESFQKRSDYESKG---IKAHFNMD 544

  Fly   482 ANGIL---------------------------------------------NVT------------ 489
            .:|:|                                             |.|
 Frog   545 ESGLLTLDRVEAVFETVVDEKPEQESTLTKLGNTISSLFGGGSSVPETKENATDSVQEEDEVPTE 609

  Fly   490 -----------ALERSTNKENKITITNDKGRLSKED----------------------------- 514
                       |.::..:||...|.||::....||:
 Frog   610 PTKEEEQESADAADKQKDKEKGTTATNEEEEGKKEEEKSEPQEEKEKQETGKEEASAKAPEVDAK 674

  Fly   515 ---------------IERMVNE-------------------AEKYRNEDEKQKETIAAKNGLESY 545
                           :|:.:|:                   .|:..|:.|::|    |.|.||::
 Frog   675 KHTAPKKQKLVDDIGVEQTLNDIPDFSEEELKKASKKLQDLTERDLNKHEREK----AANSLEAF 735

  Fly   546 CFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWL-DANQLADKEEYEHRQKELEGVCNPIITK 609
            .|..:..|::|..|...:...|..|..|.::...|| :....|..:|.:.:..||:.:|..:..|
 Frog   736 IFETQDKLNQDEFKQVSTTEQREEISAKLSQASTWLEEEGYAAITKELKDKLSELKKICKALFFK 800

  Fly   610 LYQGAGFP 617
            :.:...:|
 Frog   801 VEERRKWP 808

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_524356.1	PTZ00009	1..612	CDD:240227	190/781 (24%)
hyou1	NP_001263614.1	ASKHA_NBD_HSP70_HYOU1	34..422	CDD:466828	128/388 (33%)
		PTZ00121	<602..806	CDD:173412	33/207 (16%)