Protein Alignment Hsc70-4 and hspa12b

DIOPT Version :10

• Sequence 1: NP_524356.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001036151.1
• Gene: hspa12b / 735291
• ZFINID: ZDB-GENE-070226-1
• Length: 691
• Species: Danio rerio
• Alignment Length: 648
• Identity: 133/648 - (20%)
• Similarity: 230/648 - (35%)
• Gaps: 206/648 - (31%)

  Fly     7 VGIDLGTT---YSCVGVFQHGKVEIIANDQG------NRTTPSYVAFTDTERL--IGDAAKNQV- 59
            |.||.|||   |:...:.....:.::...:|      |:.:|:.:..|...|.  .|.||::..
Zfish    63 VAIDFGTTSSGYAFSFIEDPETIHMMRRWEGGDPGVANQKSPTCLLLTPDLRFHSFGFAARDSYH 127

  Fly    60 AMNPTQT----IFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEIS 120
            .::|.:.    .||..::......|..:::::     |.||......|||.  .....||.|.
Zfish   128 DLDPEEARHWLYFDKFKMKIHSTSDLTMETEL-----ESVSGRRVQAIEVF--AHALRFFREH-- 183

  Fly   121 SMVLTKMKETAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGL------NVLRIINEPTAA 179
              .|.::|:.:.:.|.......||||||.:....:|..::|..:|||      ..|.|..||.||
Zfish   184 --ALKEVKDQSSSVLEGNEVRWVITVPAVWRQPAKQFMREAAYLAGLVPPDSPEQLLIALEPEAA 246

  Fly   180 AI--------------------AYGLD------------------------------------KK 188
            :|                    .:.:|                                    :.
Zfish   247 SIYCRKLRLHQVTDLSQRPVTNGFDIDGSRPFDSSFRQAREQLRRARHSRTFLVESGTGELWSEM 311

  Fly   189 AVGERNVLIFDLGGGTFDVSILSID--DGIFE--VKSTAGDTHLGGED--FDNRLV----THFVQ 243
            ..|:| .::.|.||||.|:::..|:  .|..:  .|::.|.....|.|  |:..|.    |.|:.
Zfish   312 QTGDR-YIVADCGGGTVDLTVHQIEQPQGTLKELYKASGGPYGAVGVDLAFETMLCQIFGTDFID 375

  Fly   244 EFKRKHKK---DLTTNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGTDFY---------TS 296
            .||.|...   |||          .|.|..|||.:.....::.|...|...|||         |:
Zfish   376 SFKAKRPAAWVDLT----------IAFEARKRTAAPGRANTLNISLPFSFIDFYKQHRGQSVETA 430

  Fly   297 ITRARFE--------------ELNADLFRSTMDPVEKALRDAKLDKSV--IHDIVLVGGSTRIPK 345
            :.::...              |...:||:.|::.:.|.:.:....:.|  :..:.||||....|.
Zfish   431 LRKSNMNFIKWSSQGMLRLSTEATNELFQPTINNIIKHIENVMQKEEVKGVRFLFLVGGFAESPM 495

  Fly   346 VQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQDLLLLDVT-------PLSLGI 403
            :||.:|:.. |:.....|..|..:   ..::.|:|.|           ||.|       ||:.|:
Zfish   496 LQRAIQNTL-GRNCRIIIPHDVGL---TILKGAVLFG-----------LDPTVVRVRRCPLTYGV 545

  Fly   404 ETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEG--------ERAMTKDNNL-LGKF 459
                ||::..::                 ...|...:.:.:|        :|.::.|.:: ||:.
Zfish   546 ----GVLNRFVE-----------------GRHPHDKLLIKDGREWCTDILDRFVSVDQSVALGEV 589

  Fly   460 ELSGIPPAPRGVPQI----------EVTFDIDAN----GILNVTALERSTNKENKITITNDKG 508
            ......||..|..:|          ::|:..|..    |.:.:..||  :.:.:..|..||||
Zfish   590 VRRSYTPARMGQRKIIINIYCSDTDDITYITDPGVRKCGAITLDLLE--SGEASASTGDNDKG 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_524356.1	PTZ00009	1..612	CDD:240227	133/648 (21%)
hspa12b	NP_001036151.1	ASKHA_NBD_HSP70_HSPA12B	61..528	CDD:466842	104/490 (21%)