Protein Alignment Hsc70-4 and hspa8b

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001186941.1
• Gene: hspa8b / 562935
• ZFINID: ZDB-GENE-121214-31
• Length: 647
• Species: Danio rerio
• Alignment Length: 651
• Identity: 545/651 - (83%)
• Similarity: 600/651 - (92%)
• Gaps: 4/651 - (0%)

  Fly     1 MSKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQ 65
            |||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|||.
Zfish     1 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPTN 65

  Fly    66 TIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKET 130
            |:|||||||||:||||.||||||||||.|::.:.:||::|.||.|.|||:|||:||||||||||.
Zfish    66 TVFDAKRLIGRRFDDAVVQSDMKHWPFTVINDNLRPKVQVEYKGETKTFYPEEVSSMVLTKMKEI 130

  Fly   131 AEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNV 195
            ||||||||:|||||||||||||||||||||||||:|||||||||||||||||||||||...||||
Zfish   131 AEAYLGKTITNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGSERNV 195

  Fly   196 LIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRAL 260
            |||||||||||||||:|:|||||||||||||||||||||||:||||:.|||||:|||::.||||:
Zfish   196 LIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVTHFISEFKRKYKKDISDNKRAV 260

  Fly   261 RRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAK 325
            |||||||||||||||||||||||||||:||.||||||||||||||||||||.|:|||||:|||||
Zfish   261 RRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKSLRDAK 325

  Fly   326 LDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQD 390
            ||||.:||||||||||||||:|:||||.|||||||||||||||||||||||||||.||||:.|||
Zfish   326 LDKSQVHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILCGDKSENVQD 390

  Fly   391 LLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNL 455
            ||||||||||||||||||||::|||||||||||||||||||.|||||||||||||||||||||||
Zfish   391 LLLLDVTPLSLGIETAGGVMTILIKRNTTIPTKQTQTFTTYCDNQPGVLIQVYEGERAMTKDNNL 455

  Fly   456 LGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVN 520
            ||||||:|||||||||||||||||||||||:||:|:::||.|||||||||||||||||||||||.
Zfish   456 LGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQ 520

  Fly   521 EAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQ 585
            |||||:.||:.|:|.::||||||||.||||:|::::.||.|||:.|:..|::||||.|.|||.||
Zfish   521 EAEKYKAEDDVQREKVSAKNGLESYSFNMKSTVEDEKLKGKISEEDKQKIINKCNEVISWLDKNQ 585

  Fly   586 LADKEEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGGPGGMPGAAGAAGAAGAGGAGPTIEEV 650
            .|:|||:||:|||||.:|||||||||||.|..|.||||  ||.|||.||.|  |.|.:|||||||
Zfish   586 TAEKEEFEHQQKELEKLCNPIITKLYQGTGGMPEGMPG--GGFPGAGGAPG--GGGSSGPTIEEV 646

  Fly   651 D 651
            |
Zfish   647 D 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	518/610 (85%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	329/374 (88%)
hspa8b	NP_001186941.1	PTZ00009	1..613	CDD:240227	519/611 (85%)
		HSPA1-2_6-8-like_NBD	6..380	CDD:212675	328/373 (88%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	1033	1.000	Domainoid score	I26
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H136446
Inparanoid	1	1.050	1097	1.000	Inparanoid score	I231
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	1	1.000	-	-		mtm6456
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	1	1.100	-	-	LDO	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X148
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.880