Protein Alignment Hsc70-4 and hspa12a.2

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: XP_003198604.1
• Gene: hspa12a.2 / 559237
• ZFINID: ZDB-GENE-061009-20
• Length: 571
• Species: Danio rerio
• Alignment Length: 607
• Identity: 125/607 - (20%)
• Similarity: 230/607 - (37%)
• Gaps: 175/607 - (28%)

  Fly     7 VGIDLGTTYSCVGVF----QHGKVEIIAN---DQGNRT--TPSYVAFTDTE--RLIGDAAKNQVA 60
            :.||.||:||...:.    |..:..:|.|   |.|..|  ||:.:.|.:.|  :..|
Zfish     8 IAIDFGTSYSGYAISFKTKQPQESILIPNWGVDYGYNTFKTPTCILFDEHETFQKFG-------- 64

  Fly    61 MNPTQTIFDAKRLIGRKFDDAAVQSD------MKHWPFEVVSADGKPKIEVTYKD----EKKTFF 115
                   :||.....|    :.|:|.      .:|:..|:...:....:.:|.|:    :..|.|
Zfish    65 -------YDAMMTYTR----STVKSQARKSFLFEHFKMELYDKEIHRDLMITAKNGGQMKALTVF 118

  Fly   116 PEEISSM---VLTKMKE--TAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNV------ 169
            .|.:..:   .|.|:||  |.:.::...|| .|:||||.:|.:.:|..::|...|||.:
Zfish   119 SESLRYLKDHALEKVKENPTGKTFIASDVT-WVLTVPAIWNAAAKQFMREAAIEAGLVIESEPER 182

  Fly   170 LRIINEPTAAAI--------AYGLDKKAVGE-------RNVLIFDLGGGTFDVSILS-IDDGIFE 218
            |....||.||:|        .| :.::|..:       ...::.|.||||.|:::.. ::||..:
Zfish   183 LVFALEPEAASIYCKHLPSEGY-ISEEACRDTLEQKPGTQYMVVDCGGGTIDITVHEVVEDGKLK 246

  Fly   219 VKSTAGDTHLGGEDFDNRLVTH----FVQEFKRKHKKDLTTNKRALR---RLRTACE-----RAK 271
            ..:.|....:||:..|.:.::.    |.::...|.::|.......|:   .|..:|:     :..
Zfish   247 ELNAASGNDMGGQTVDRKFISFLKEIFSEKIYNKFEQDFPAEALKLKYDIALAKSCDQLVLIQCP 311

  Fly   272 RTLSSSTQASIEIDSLFEGT------DFYTSITRARFEELNADLFRSTMDPVEKALRDAKLDKSV 330
            .||....:....|:|.|||.      :....|...:.:....:..::|.:.:||...:.:|:
Zfish   312 VTLQELAKKEKAIESYFEGVEGAEWDEGSIIIKEDKLQSFFDESLKTTAEKLEKITSNPELN--- 373

  Fly   331 IHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPD---------------------EAVAYGAA 374
            |..::||||......:::.|::.|:..::...:.|.                     .|:.||..
Zfish   374 IEYMLLVGGFAECKILKKFLKERFDKCKIVCPVEPQVVIIKGAIRYAKQPKVVKSRMSALTYGIR 438

  Fly   375 VQA---AILHGDKSQEVQDLLLLDVTPLSLGIETAGGVMSVLIKRNTTI-----------PTKQT 425
            :.|   .:||.|||..|.          |.|...........:::..::           |:...
Zfish   439 IDAPFDKVLHKDKSNYVN----------SEGQTYCDVCFETFVRKGESVNCDEVRQFFFNPSHTN 493

  Fly   426 QT---FTTYSDN--------QPGVLIQVYEGERAMTKDNNLLGKFELSGIPPAPRGVP---QIEV 476
            ||   |..:|.|        :|||               ..:|.||: |:|....|:.   ::|:
Zfish   494 QTSAIFQFFSTNEKQVQFIDEPGV---------------EPVGFFEV-GMPKTDGGLSREIKLEI 542

  Fly   477 TF----------DIDANGILNV 488
            .|          |:|:....:|
Zfish   543 KFGSTEMKATATDVDSGETTSV 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	125/607 (21%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	97/463 (21%)
hspa12a.2	XP_003198604.1	HSPA12_like_NBD	6..420	CDD:212671	93/435 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900