Protein Alignment Hsc70-4 and hspa12a.1

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001038342.1
• Gene: hspa12a.1 / 558896
• ZFINID: ZDB-GENE-061009-21
• Length: 571
• Species: Danio rerio
• Alignment Length: 605
• Identity: 124/605 - (20%)
• Similarity: 232/605 - (38%)
• Gaps: 171/605 - (28%)

  Fly     7 VGIDLGTTYSCVGVF----QHGKVEIIAN---DQGNRT--TPSYVAFTDTE--RLIGDAAKNQVA 60
            :.||.||:||...:.    |..:...|.|   :.|..|  ||:.:.|.:.|  :..|
Zfish     8 IAIDFGTSYSGYAISFKTKQPQESIQIPNWGVNFGYNTFKTPTCILFDEHETFQKFG-------- 64

  Fly    61 MNPTQTIFDAKRLIGRKFDDAAVQSD--MKHWPFEVVSADGKPKIEVTYKD----EKKTFFPEEI 119
                   :||.....|....:..:..  .:|:..|:...:....:.:|.|:    :..|.|.|.:
Zfish    65 -------YDAMMTYTRSTPKSQARKSFLFEHFKMELYDKEIHRDLMITAKNGGQMKALTVFSESL 122

  Fly   120 SSM---VLTKMKE--TAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNV------LRII 173
            ..:   .|.|:||  |.:.::...|| .|:||||.:|.:.:|..::|...|||.:      |...
Zfish   123 RYLKDHALEKIKENTTGKTFIASDVT-WVLTVPAIWNAAAKQFMREAAIEAGLVIESEPERLVFA 186

  Fly   174 NEPTAAAI--------AYGLDKKAVGE-------RNVLIFDLGGGTFDVSILS-IDDGIFEVKST 222
            .||.||:|        .| :.::|..:       ...::.|.||||.|:::.. ::||..:..:.
Zfish   187 LEPEAASIYCKHLPSEGY-ISEEACRDTLEQKPGTQYMVVDCGGGTIDITVHEVVEDGKLKELNA 250

  Fly   223 AGDTHLGGEDFDNRLVTHFVQEFKRK--HKKDLTTNKRALR-----RLRTACE-----RAKRTLS 275
            |....:||:..|.:.::...:.|..|  :|.:......||:     .|..:|:     :...||.
Zfish   251 ASGNDMGGQTVDRKFISFLKEIFSEKIYNKFEQNFPAEALKLKYDIALAKSCDQLVLIQCPVTLQ 315

  Fly   276 SSTQASIEIDSLFEGT------DFYTSITRARFEELNADLFRSTMDPVEKALRDAKLDKSVIHDI 334
            ...:....|:|.|||.      :....|...:.:....:..::|.:.:||.:.:.:|:   |..:
Zfish   316 ELAKKEKAIESYFEGVEGAEWDEGSIIIKEDKLQSFFDESLKTTAEKLEKIMSNPELN---IEYM 377

  Fly   335 VLVGGSTRIPKVQRLLQDLFNGKELNKSINPD---------------------EAVAYGAAVQA- 377
            :||||......:::.|::.|:..::...:.|.                     .|:.||..:.|
Zfish   378 LLVGGFAECKILKKFLKERFDKCKIVCPVEPQVVIIKGAIRYAKQPKVVKSRMSALTYGIRIDAP 442

  Fly   378 --AILHGDKSQEV--QDLLLLDVTPLSLGIETAGGVMSVLIKRNTTI-----------PTKQTQT 427
              .:||..|:..|  :.....||.     .||       .:::..::           |:...||
Zfish   443 FDEVLHKGKTSYVNSERQTYCDVC-----FET-------FVRKGESVNCDEVRHFFFNPSHTNQT 495

  Fly   428 FTT---YSDN--------QPGVLIQVYEGERAMTKDNNLLGKFELSGIPPAPRGVP---QIEVTF 478
            |.|   :|.|        :|||               .|:|.|:: |:|....|:.   ::|:.|
Zfish   496 FATFQFFSTNEKQVQFIDEPGV---------------ELVGVFQV-GMPKTDGGLSREIKLEIKF 544

  Fly   479 ----------DIDANGILNV 488
                      |:|:....:|
Zfish   545 GSTEMKATATDVDSGETTSV 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	124/605 (20%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	95/459 (21%)
hspa12a.1	NP_001038342.1	HSPA12_like_NBD	6..420	CDD:212671	91/431 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910