Protein Alignment Hsc70-4 and hsph1

DIOPT Version :10

• Sequence 1: NP_524356.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: XP_001919957.3
• Gene: hsph1 / 557824
• ZFINID: ZDB-GENE-120410-4
• Length: 866
• Species: Danio rerio
• Alignment Length: 699
• Identity: 212/699 - (30%)
• Similarity: 344/699 - (49%)
• Gaps: 108/699 - (15%)

  Fly     7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDAK 71
            ||.|:|....|:.|.:.|.:|.::|:..:|.|||.::|....|.||:|||||:..||:.|:|..|
Zfish    31 VGFDVGFQNCCIAVVKSGGIETVSNEFTDRCTPSVISFGSKNRAIGNAAKNQMITNPSSTVFHFK 95

  Fly    72 RLIGRKFDDAAVQSDMKHWPFEVVSA-DGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAEAYL 135
            ||..|.:.|..||::..:.|:::|.. |||..::|.|.|::..|..|:||:|:|||:|:.|||.|
Zfish    96 RLHSRLYHDKVVQAEKANLPYDLVPLNDGKVGVQVMYLDQEHHFSIEQISAMLLTKLKDIAEANL 160

  Fly   136 GKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAV--GERN---V 195
            .|.|...||::|::|.||:|::..||..|||||.|:::|:.||.|:.||:.|:.:  .:.|   |
Zfish   161 QKKVLECVISIPSFFTDSERRSVLDAAKIAGLNCLKLMNDSTAVALNYGIYKEDLPGSDENPKIV 225

  Fly   196 LIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRAL 260
            ...|||...|.|||.:.:.|..:|.|||.|.:|||:|||.|||.||..|||.|:..|:.:..|||
Zfish   226 AFVDLGHSAFQVSICAFNRGKVKVLSTAFDPYLGGKDFDQRLVDHFCAEFKSKYMMDVKSKTRAL 290

  Fly   261 RRLRTACERAKRTLSS-STQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDA 324
            .||...||:.|:.:|| ||:.|:.|:...:..|....:.||:|||:.|||.......:.||:..|
Zfish   291 LRLTQECEKLKKLMSSNSTELSLNIECFIDDKDVCGRMNRAKFEEMCADLIERVKFTLMKAVEQA 355

  Fly   325 KLDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQ 389
            .:....|..:.:|||:||||.|:..:...|. ::::.::|.|||||.|.|:|.|:|  ..:..|:
Zfish   356 GVRLQDISAVEIVGGATRIPAVKAQISSFFR-RDVSTTLNADEAVARGCALQCAML--SPAFRVR 417

  Fly   390 DLLLLDVTPLSLGIETA-----GGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAM 449
            :..:.||.|..:.:..:     |.....:..||...|:.:..||..   |:|.:|...|..:.::
Zfish   418 EFSITDVIPFPISLSWSSEADEGKSCHEIFSRNHPCPSAKMITFYR---NKPFILEAFYSDKSSL 479

  Fly   450 TKDNNLLGKFELSGIPPAP-RGVPQIEVTFDIDANGILNVTA----------------------- 490
            ......:|::::..|.|.. |...:::|..:::.:|:::|::
Zfish   480 PFPEAKIGEYKVQNIQPQENREKAKVKVKVEVNRSGVVSVSSAAVVLRVRSDESEITEINEDVDS 544

  Fly   491 -----------------LERSTNKENKITI--------TNDKGRLS------------------- 511
                             :|.|.||||..|.        .|.:..||
Zfish   545 HDASDDTDVQDKTEEVNIELSVNKENLPTAQCPPMEKEQNQRETLSMNGEVNSHPPHAKKAKMKV 609

  Fly   512 ----------------KEDIERMVNEAEKYRNEDEKQKETIAAKNGLES--YCFNMKATLDEDNL 558
                            |:.:.....:..|...:|.::||...|||.:|.  |.|..|.   |.:.
Zfish   610 KHVVLPMEETFNQQLPKDRLSAYTEQENKMIQQDRQEKERNNAKNAVEENVYYFRHKL---EGSY 671

  Fly   559 KTKISDSDRTTILDKCNETIKWL-DANQLADKEEYEHRQKELEGVCNPI 606
            :|.::..:.....:..|.|..|| |.....||:.|.:|..|:..:..|:
Zfish   672 QTFLNAQEHQAFSELLNGTENWLYDEGADQDKQTYINRLAEIHKLGLPV 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_524356.1	PTZ00009	1..612	CDD:240227	212/699 (30%)
hsph1	XP_001919957.3	ASKHA_NBD_HSP70_HSPH1	29..408	CDD:466845	154/377 (41%)