Protein Alignment Hsc70-4 and Hspa14

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_056580.2
• Gene: Hspa14 / 50497
• MGIID: 1354164
• Length: 509
• Species: Mus musculus
• Alignment Length: 508
• Identity: 172/508 - (33%)
• Similarity: 287/508 - (56%)
• Gaps: 15/508 - (2%)

  Fly     6 AVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDA 70
            |:|:.||.|.:||.|::.|:.:::|||.|:|.||:.||:::.|:::|.|||.....:.:.|:...
Mouse     3 AIGVHLGCTSACVAVYKDGRADVVANDAGDRVTPAIVAYSEREQVVGLAAKQSRIRHVSSTVVKV 67

  Fly    71 KRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAEAYL 135
            |:::||...|...|..:......|:..:||.:.|:...:|.|...||:::.::.:||||||.:.|
Mouse    68 KQILGRSSADPQAQKYISESKCLVIEKNGKLRYEIDTGEETKLVNPEDVARLIFSKMKETAHSVL 132

  Fly   136 GKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDK-KAVGERNVLIFD 199
            |....:.|:|||..|.:.|:.|..:|...||.||||:|:||:||.:|||:.: ...|:.|||:|.
Mouse   133 GSDANDVVVTVPFDFGEKQKSALGEAAGAAGFNVLRLIHEPSAALLAYGIGQDHPTGKSNVLVFK 197

  Fly   200 LGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRRLR 264
            |||.:..:|::.::.|::.|.||....::||..|.:.|..:...||:|..|.|:..|.||:.:|.
Mouse   198 LGGTSLSLSVMEVNSGMYRVLSTNTSDNIGGAHFTDTLAQYLASEFQRLFKHDVRGNARAMMKLM 262

  Fly   265 TACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAKLDKS 329
            .:.|.||.:||:...|:..:|||:||.||..:::|||||.|.:.||....:.:.:.||.......
Mouse   263 NSAEVAKHSLSTLGSANCFVDSLYEGQDFDCNVSRARFELLCSPLFNKCTEAIRELLRQTGFTAD 327

  Fly   330 VIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQDLLLL 394
            .|:.:||.|||:||||:|:|::|||...:|..||.|||.:..|||::|.||.|.:|....|.:::
Mouse   328 DINKVVLCGGSSRIPKLQQLIKDLFPAVDLLNSIPPDEVIPIGAAIEAGILVGKESTSGDDSVMI 392

  Fly   395 DVTP---LSLGIETAGG-VMSVLIKRNTTIPTKQTQTFTTYSDNQPG----VLIQVYEGE-RAMT 450
            :.:.   |..|::.:|. ..:||....|.:|.::..|.     ..||    |.:::||.| :...
Mouse   393 ECSAKDILVKGVDESGADRFTVLFPSGTPLPARRQHTL-----QAPGRVSSVCLELYESEGKNSA 452

  Fly   451 KDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITI 503
            |:.....:..|..:.....|:..|.....:..:|.|.||..::.|.|...||:
Mouse   453 KEEAKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLQVTCTDQDTGKCEAITV 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	172/508 (34%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	142/375 (38%)
Hspa14	NP_056580.2	HSPA14-like_NBD	2..376	CDD:212680	140/372 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810