Protein Alignment Hsc70-4 and AgaP_AGAP007682

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: XP_001237047.2
• Gene: AgaP_AGAP007682 / 4576741
• VectorBaseID: AGAP007682
• Length: 1169
• Species: Anopheles gambiae
• Alignment Length: 600
• Identity: 238/600 - (39%)
• Similarity: 354/600 - (59%)
• Gaps: 71/600 - (11%)

  Fly     6 AVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDA 70
            |:|||.||::|.||::::||.|||||:.||...||.||||:..||:|:.|..|...:|...:.:.
Mosquito    29 AIGIDFGTSFSSVGIYRNGKFEIIANECGNHRIPSVVAFTEKGRLVGEEALAQADTDPANCVIEV 93

  Fly    71 KRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAEAYL 135
            ||::||...:..:|                    |.:|.|.|.:.||||..::|..::..||..|
Mosquito    94 KRILGRHKKEGGLQ--------------------VQFKGETKCYQPEEICGIILAHLRSMAERQL 138

  Fly   136 GKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNVLIFDL 200
            |:.||.||:.|||.|:|.||||..||.|||||:|||:|||||||||:.|::||.:||:.||:...
Mosquito   139 GEPVTCAVVAVPAQFSDGQRQAVLDAATIAGLSVLRLINEPTAAAISIGINKKLIGEQYVLVCSF 203

  Fly   201 GGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRRLRT 265
            |||..||||::|.:|:|:||:::|||.|||.|.|.|||.:||:|.:.....|:|.:..|:|:||.
Mosquito   204 GGGFLDVSIVTIYNGVFQVKASSGDTRLGGVDIDKRLVDYFVKELQDTQSLDITRDCIAMRKLRK 268

  Fly   266 ACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAKLDKSV 330
            .||:||||||.::|.::|||.|.:|....:::|:...:||..|||...:..||.|||.|:.|:..
Mosquito   269 TCEQAKRTLSYTSQVTVEIDDLLDGHKLSSTLTKDNVDELCKDLFERVILHVETALRRARKDRFA 333

  Fly   331 IHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQDLLLLD 395
            :|:|:|||.|:|||:||.:|.:.|:.:.|:.|:|.||||..|.|:.|.||.||||..:||||..|
Mosquito   334 MHEIMLVGESSRIPRVQIMLSEFFDRRSLSSSVNSDEAVVVGTAIAAGILSGDKSCAIQDLLWWD 398

  Fly   396 VTPLSLGIET---------AGGVMS----VLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGER 447
            :.|.|:|:.:         .||.:.    :||.||:|:|.|.......:.:     :.::||||.
Mosquito   399 LVPRSIGMISEELDIDGGDGGGDVGEPPRILISRNSTLPLKVRHRVKNFRN-----VHRLYEGES 458

  Fly   448 AMTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSK 512
            |:..||..||:.:|.|  ....|:..:.::|::|.||:|:|..   ..|.|.|.|:  |||||.:
Mosquito   459 AIVSDNITLGRLQLEG--SFGEGLEDVGLSFNVDLNGVLHVMV---EGNIELKATL--DKGRLER 516

  Fly   513 EDIERMVNE-----AEKYRNEDE----KQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRT 568
            .:|:|:|.|     .|..|.::|    |:|||            :..|.:|....:.:....|..
Mosquito   517 YEIDRIVYEHKRLILEMERGQEEQEQRKRKET------------DHSAVIDRQGEEQEAEADDGG 569

  Fly   569 TI--LDKCNETIKWL 581
            |:  .|:.:|   ||
Mosquito   570 TVGTWDRFSE---WL 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	237/599 (40%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	170/374 (45%)
AgaP_AGAP007682	XP_001237047.2	prok_dnaK	29..568	CDD:274091	232/582 (40%)
		NBD_sugar-kinase_HSP70_actin	29..384	CDD:302596	170/374 (45%)
		DENN	691..>850	CDD:299760
		SPA	799..902	CDD:285780

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820