Protein Alignment Hsc70-4 and Hsc70Cb

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001189103.1
• Gene: Hsc70Cb / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Alignment Length: 690
• Identity: 196/690 - (28%)
• Similarity: 333/690 - (48%)
• Gaps: 101/690 - (14%)

  Fly     7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDAK 71
            :|||.|.....|...:.|.:|.:|||...|.|||:|||...:|:||.|||||...|...|:...|
  Fly     4 IGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTVGGFK 68

  Fly    72 RLIGRKFDDAAVQSDMKHWPFEV-VSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAEAYL 135
            ||:||||:|..||.::...|..| ...||...|:|.|..|.:.|.||::::|:.||:|||:.|.:
  Fly    69 RLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETSAAAM 133

  Fly   136 GKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGE---RNVLI 197
            ...|.:.||..|.:|.:::|:|..||..||||||||::||.||.|:|||..|..:.|   |||:.
  Fly   134 QTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFEDKPRNVIF 198

  Fly   198 FDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRR 262
            .|.|..:...|..:...|..::.::..| .:||.|.|..|..:|.:||:.::|.:..||.||..|
  Fly   199 VDFGHSSLQASACAFTKGKLKMLASTWD-QIGGRDIDLALGDYFAKEFQERYKINAKTNARANLR 262

  Fly   263 LRTACERAKRTLS-SSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAKL 326
            |.|..|:.|:.:| :||:..:.|:...:..|..:|:.|::.|||.|.:.:......::.|.::||
  Fly   263 LLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSSSMQRSQMEELCAPVLQRVEQTFKRLLAESKL 327

  Fly   327 DKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQDL 391
            ....||.:.:||||:|||.|::|::.:|| |..:.::|.||||:.|||:|.||:  ..:..|::.
  Fly   328 QLDDIHSVEIVGGSSRIPSVKQLIEQVFN-KPASTTLNQDEAVSRGAALQCAIM--SPAVRVREF 389

  Fly   392 LLLDVTPLSLGI------ETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVL-IQVYEGERAM 449
            .:.|:...::.:      ..|.|.:.:..:.:.: |..:..|.     |:.|.. :.:..|::..
  Fly   390 GVTDIQNYAVKVLWDSEGSAAPGEIEIFPQYHAS-PFSRLLTI-----NRKGPFNVSIVYGQQVP 448

  Fly   450 TKDNNLLGKFELSGIPPAPRGVPQ-IEVTFDIDANGILNVT---------------ALERSTNKE 498
            ..|.. :|.:::..:.|..||..| :::...|:.|||:.::               |.|::.::|
  Fly   449 YPDQT-IGVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISSATLVEKKEAEEAAAAAEQAASEE 512

  Fly   499 NKITITNDKGR------------------------------------------------------ 509
            .....||:.|.
  Fly   513 KPGDQTNNTGEPADGQQEAYCENEDDNNTSTASSPGGQGWAQRVKGWFGSGADKKKKASKATELP 577

  Fly   510 -------LSKEDIERMVNEAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDR 567
                   .|..|:.....:..|....|:|:.|.|.|||.||.:.::|:..|.....:..:.:::|
  Fly   578 LECTTHGFSPVDLSNYTQQESKMIGNDQKETERIDAKNALEEFVYDMRNKLQGGPFERYVVEAER 642

  Fly   568 TTILDKCNETIKWL-DANQLADKEEYEHRQKELEGVCNPI 606
            ..|:.:.|:...|| :..:..:::.|..|.:.|....:||
  Fly   643 EKIVSQLNDLENWLYEDGEDCERDIYTSRLQALHQKTDPI 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	196/690 (28%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	147/378 (39%)
Hsc70Cb	NP_001189103.1	HSPA4_like_NDB	2..381	CDD:212670	147/380 (39%)
		HSP70	3..682	CDD:278441	194/688 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464198
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740