Protein Alignment Hsc70-4 and hspa9

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_958483.2
• Gene: hspa9 / 373085
• ZFINID: ZDB-GENE-030828-12
• Length: 682
• Species: Danio rerio
• Alignment Length: 653
• Identity: 320/653 - (49%)
• Similarity: 429/653 - (65%)
• Gaps: 43/653 - (6%)

  Fly     3 KAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTQT 66
            :...:|||||||.|||.|......:::.|.:|.|||||.|||| |.|||:|..||.|...||..|
Zfish    55 RGAVIGIDLGTTNSCVAVMDGKNAKVLENAEGARTTPSVVAFTSDGERLVGMPAKRQAVTNPNNT 119

  Fly    67 IFDAKRLIGRKFDDAAVQSDMKHWPFEVVSA-DGKPKIEVTYKDEKKTFFPEEISSMVLTKMKET 130
            ::..||||||:||||.||.|:|:.|:::|.| :|...:||    ..|.:.|.:..:.:|.|||||
Zfish   120 LYATKRLIGRRFDDAEVQKDLKNVPYKIVRASNGDAWLEV----HGKMYSPSQAGAFILIKMKET 180

  Fly   131 AEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNV 195
            ||:|||::|.|||:||||||||||||||||||.||||||||:||||||||:||||||  ..::.:
Zfish   181 AESYLGQSVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGLDK--TQDKII 243

  Fly   196 LIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRAL 260
            .::||||||||:|:|.|..|:||||||.|||.|||||||..|:.|.|:|||::...||..:..||
Zfish   244 AVYDLGGGTFDISVLEIQKGVFEVKSTNGDTFLGGEDFDQHLLRHIVKEFKKESGVDLMKDNMAL 308

  Fly   261 RRLRTACERAKRTLSSSTQASIEIDSLFEGTD----FYTSITRARFEELNADLFRSTMDPVEKAL 321
            :|:|.|.|:||..||||.|..|.:..|.....    ....:||::||.:.|||.|.|:.|.:||:
Zfish   309 QRVREAAEKAKCELSSSLQTDINLPYLTMDASGPKHLNMKLTRSQFEGIVADLIRRTVAPCQKAM 373

  Fly   322 RDAKLDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQ 386
            :||::.||.|.:::||||.||:||||:.:|||| |:..:||:|||||||.|||:|..:|.||
Zfish   374 QDAEVSKSDIGEVLLVGGMTRMPKVQQTVQDLF-GRAPSKSVNPDEAVAIGAAIQGGVLAGD--- 434

  Fly   387 EVQDLLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTK 451
             |.|:||||||||||||||.|||.:.||.||||||||::|.|:|.:|.|..|.|:|.:|||.|..
Zfish   435 -VTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAT 498

  Fly   452 DNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIE 516
            ||.:||:|.|.|||||.|||||||||||||||||::|:|.::.|.:|.:|.| ...|.|||:|||
Zfish   499 DNKVLGQFTLVGIPPALRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIE 562

  Fly   517 RMVNEAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDE--DNLKTKISDSDRTTILDKCNETIK 579
            .||..||||..||.::|:.:.|.|..|....:.::.::|  |.|..           |:||:..:
Zfish   563 NMVKNAEKYAEEDRRRKDRVEAVNMAEGIVHDTESKMEEFKDQLPA-----------DECNKLKE 616

  Fly   580 WLD-ANQLADKEEYEHRQ--KELEGVCNPIITKLYQGAGFPPGGMPGGPGGMPGAAGAAGAAGAG 641
            .:. ..:|..:::.|..:  |:..........||::.|......         ...|::|::.:|
Zfish   617 EISKVRELLSRKDTETGENIKQAATSLQQASLKLFEMAYKKMAS---------EREGSSGSSSSG 672

  Fly   642 GAG 644
            .||
Zfish   673 EAG 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	314/619 (51%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	206/380 (54%)
hspa9	NP_958483.2	HSPA9-like_NBD	55..431	CDD:212683	206/382 (54%)
		dnaK	56..659	CDD:234715	315/625 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820