| Sequence 1: | NP_001262586.1 | Gene: | Hsc70-4 / 41840 | FlyBaseID: | FBgn0266599 | Length: | 651 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_006588.1 | Gene: | HSPA8 / 3312 | HGNCID: | 5241 | Length: | 646 | Species: | Homo sapiens |
| Alignment Length: | 654 | Identity: | 555/654 - (84%) |
|---|---|---|---|
| Similarity: | 600/654 - (91%) | Gaps: | 11/654 - (1%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1 MSKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQ 65
Fly 66 TIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKET 130
Fly 131 AEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNV 195
Fly 196 LIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRAL 260
Fly 261 RRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAK 325
Fly 326 LDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQD 390
Fly 391 LLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNL 455
Fly 456 LGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVN 520
Fly 521 EAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQ 585
Fly 586 LADKEEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGG-PGGMPGAAGAAGAAGAGGA--GPTI 647
Fly 648 EEVD 651 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Hsc70-4 | NP_001262586.1 | PTZ00009 | 1..612 | CDD:240227 | 528/610 (87%) |
| HSPA1-2_6-8-like_NBD | 6..381 | CDD:212675 | 334/374 (89%) | ||
| HSPA8 | NP_006588.1 | PTZ00009 | 1..613 | CDD:240227 | 529/611 (87%) |
| Nucleotide-binding domain (NBD). /evidence=ECO:0000305|PubMed:27474739 | 2..386 | 341/383 (89%) | |||
| Interaction with BAG1 | 186..377 | 169/190 (89%) | |||
| Substrate-binding domain (SBD). /evidence=ECO:0000305|PubMed:27474739 | 394..509 | 107/114 (94%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 614..646 | 23/39 (59%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 1030 | 1.000 | Domainoid score | I26 |
| eggNOG | 1 | 0.900 | - | - | E1_COG0443 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 1099 | 1.000 | Inparanoid score | I234 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S49 |
| OMA | 1 | 1.010 | - | - | QHG53894 | |
| OrthoDB | 1 | 1.010 | - | - | D180577at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000049 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41703 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100083 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR19375 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R573 |
| SonicParanoid | 1 | 1.000 | - | - | X148 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.860 | |||||