Protein Alignment Hsc70-4 and CG2918

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001162645.1
• Gene: CG2918 / 31215
• FlyBaseID: FBgn0023529
• Length: 923
• Species: Drosophila melanogaster
• Alignment Length: 745
• Identity: 182/745 - (24%)
• Similarity: 312/745 - (41%)
• Gaps: 148/745 - (19%)

  Fly     4 APAVGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTI 67
            |..:.:|||:.:..|||...| .:||..|.:..|.||:.:||.|..|.||:.|:.....:|....
  Fly    20 AAVMSVDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAILAFRDGTRTIGEDAQTIGIKDPNSAY 84

  Fly    68 FDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAE 132
            .....|:|:..|:..|....|.:|:..:..|.:....|..|.:...|..||:.:.:|.|.|:.|:
  Fly    85 GYLLDLLGKTIDNPIVDLYRKRFPYYNIVGDPERNTVVFRKSDTDEFSVEELVAQLLVKAKQFAQ 149

  Fly   133 AYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERN--- 194
            ..:.:.:|..|:|||.||..::|:|...|..:|.|.||::||:..|.|:.||:..:  ||.|
  Fly   150 ESVQQPITECVLTVPGYFGQAEREALLSAAQLANLKVLQLINDYAAVALNYGVFHR--GEINETA 212

  Fly   195 --VLIFDLGGGTFDVSILSID----------DGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFK- 246
              .|.:|:|......:::|..          :.:.:|.....|..|||.:...||..:..|||.
  Fly   213 QYFLFYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGLEIQLRLRDYLAQEFNA 277

  Fly   247 -RKHKKDLTTNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLF 310
             :|.|.|:||:.|||.:|.....|.|..||::|:...:|::|.|..||...:||.:.|:|..||:
  Fly   278 LKKTKTDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDIDFKLPVTREKLEQLCEDLW 342

  Fly   311 RSTMDPVEKALRDAKLDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAV 375
            .....|:|:||..:.|...||:.::|.||.||:|:||..::.:.. :||.|::|.||:...||..
  Fly   343 PRATKPLEEALASSHLSLDVINQVILFGGGTRVPRVQETIKAVIK-QELGKNLNADESATMGAVY 406

  Fly   376 QAAILHGDKSQEVQDLLLLDVT--PLSLGIETAGG-------VMSVLIKRNTTIPTKQTQTFTTY 431
            :||.|  ....:|:..::.|.|  ||.:..|...|       |...|.......|.|:..||..:
  Fly   407 KAADL--SAGFKVKKFVVKDATLFPLQVSFERDPGDGAAVKQVKRALFALMNPYPQKKVITFNKH 469

  Fly   432 SDNQPGVLIQVY----EGERAMTKDNNLLGKFELSGIPPAPRGVPQ--------------IEVTF 478
            :|:     .:.|    :.:|...::...||...::.:  ..:.|.:              |:..|
  Fly   470 TDD-----FEFYVNYADLDRYSKEEIAALGSLNVTKV--QLKQVKELLEKSKKELVDNKGIKAYF 527

  Fly   479 DIDANGILNVTALERSTNKENKITITNDKGRLSK------------------------------- 512
            .:|.:||...|.:|....|:......::...|||
  Fly   528 YLDDSGIFRCTGVEYVYEKQKPEDDADEDSTLSKFGSTLSKLFTKEGEEKKDNSEQEEAANAGEE 592

  Fly   513 ----EDIERMVNE-AEKYRNEDEKQKETIAAK--------------------------------- 539
                ||.|:...| |.|.:..:|..|:...||
  Fly   593 PSKSEDNEKAKEEDASKEQKSEESTKQDTEAKNETIKLVTVKSPVTYESQTQFVVPLVGSAYDQS 657

  Fly   540 ---------------------NGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDA 583
                                 |.||::...::..|||::.....:..::..:|.:|:...:||..
  Fly   658 VAKLAAINKAEEQRVRLESAFNALEAHIIEVQQKLDEESYAKCATAEEKEKLLAECSTLGEWLYE 722

  Fly   584 NQLADKEE-YEHRQKELEGVCNPIITKLYQ 612
            :....|.| ||.:..:|:.:.|..:.:.::
  Fly   723 DLEDPKAEIYEEKLAQLKKLSNVFLARHWE 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	182/743 (24%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	124/392 (32%)
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	164/614 (27%)
		HYOU1-like_NBD	23..409	CDD:212672	122/388 (31%)
		TAF4	<572..>627	CDD:296797	10/54 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464221
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740