Protein Alignment Hsc70-4 and Hspa14

DIOPT Version :10

• Sequence 1: NP_524356.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001004257.1
• Gene: Hspa14 / 307133
• RGDID: 1303296
• Length: 509
• Species: Rattus norvegicus
• Alignment Length: 508
• Identity: 173/508 - (34%)
• Similarity: 288/508 - (56%)
• Gaps: 15/508 - (2%)

  Fly     6 AVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDA 70
            |:|:.||.|.:||.|::.|:.:::|||.|:|.||:.||:::.|:::|.|||.....|.:.|:...
  Rat     3 AIGVHLGCTSACVAVYKDGRADVVANDAGDRVTPAVVAYSEREQVVGLAAKQSRIRNISSTVVKV 67

  Fly    71 KRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAEAYL 135
            |:::||...|...|..:......|:..:||.:.|:...:|.|...||:::.::.:||||||.:.|
  Rat    68 KQILGRSTADPQAQKYISESKCLVIEKNGKLQYEIDTGEETKLVSPEDVARLIFSKMKETAHSVL 132

  Fly   136 GKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKA-VGERNVLIFD 199
            |....:.|:|||..|.:.|:.|..:|...||.||||:|:||:||.:|||:.:.. .|:.|||:|.
  Rat   133 GSDANDVVVTVPFDFGEKQKSALGEAAGAAGFNVLRLIHEPSAALLAYGIGQDCPTGKSNVLVFK 197

  Fly   200 LGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRRLR 264
            |||.:..:||:.::.|::.|.||....::||..|.:.|..:...||:|..|.|:..:.||:.:|.
  Rat   198 LGGTSLSLSIMEVNSGMYRVLSTNTSDNIGGVHFTDSLAQYLASEFQRLFKHDVRGSARAMMKLM 262

  Fly   265 TACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAKLDKS 329
            .:.|.||.:||:...|:..:|||:||.||..:::|||||.|.:.||...::.|...|:.:.....
  Rat   263 NSAEVAKHSLSTLGSANCFVDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAVRALLQQSGFTAD 327

  Fly   330 VIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQDLLLL 394
            .|:.:||.|||:|||::|:|::|||...:|..||.|||.:..|||::|.||.|.:|....|.:|:
  Rat   328 DINKVVLCGGSSRIPRLQQLIKDLFPAGDLLNSIPPDEVIPIGAAIEAGILVGKESTSGDDSVLI 392

  Fly   395 DVTP---LSLGIETAG-GVMSVLIKRNTTIPTKQTQTFTTYSDNQPG----VLIQVYEGE-RAMT 450
            :.:.   |..|::.:| ...:||....|.:|.::..|.     ..||    |.:::||.| :...
  Rat   393 ECSARDILVKGVDESGANRFTVLFPSGTPLPARRQHTL-----QAPGSISSVCLELYESEGKNSV 452

  Fly   451 KDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITI 503
            |:.....:..|..:.....|:..|.....:..:|.|.||..::.|.|...||:
  Rat   453 KEETKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLQVTCTDQETGKCEAITV 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_524356.1	PTZ00009	1..612	CDD:240227	173/508 (34%)
Hspa14	NP_001004257.1	ASKHA_NBD_HSP70_HSPA14	2..378	CDD:466836	141/374 (38%)