Protein Alignment Hsc70-4 and SLC9C2

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: XP_011507728.1
• Gene: SLC9C2 / 284525
• HGNCID: 28664
• Length: 1129
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 52/279 - (18%)
• Similarity: 93/279 - (33%)
• Gaps: 116/279 - (41%)

  Fly   118 EISSMVLTKMK-----------ETAEAYL-------GKTVTNAVITVPAYFNDSQRQATKDAG-- 162
            ||:.::|.|:|           .|.:.||       ||.|      :..:|.:..:.|..|:|
Human   835 EINKVLLKKLKALNNFPKAIPPPTPDIYLHNIIWLEGKDV------LIDFFKERAKLACFDSGDT 893

  Fly   163 -------------TIAGLNVLRIINEPTAAAIAYGLDKKAVGERNVLIFDLGGGTFDVSILSIDD 214
                         .|:|:.:|..:: ||     :|::.....:|         |:.|
Human   894 ICKGGEMPQGIYLIISGMAILHSLS-PT-----FGIESNQRCDR---------GSRD-------- 935

  Fly   215 GIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRRLRTACERAKRTLSSSTQ 279
             :|....|.||               .:.|.....|:::        .....||       :|.|
Human   936 -MFTEFCTTGD---------------IIGELSCLLKREI--------EYTVICE-------TSLQ 969

  Fly   280 AS-IEIDSLFEGTD-FYTSI-----------TRARF-------EEL---NADLFRSTMDPVEKAL 321
            |. |.::.|:||.| |:.|:           |..::       |:|   |..:|.........:.
Human   970 ACFISLEDLYEGFDAFWPSLEYKIWLKLALSTAYQYFESSLIDEDLRFQNCVMFNQAYVETLSSY 1034

  Fly   322 RDAKLDKSVIHDIVLVGGS 340
            .|..:|...:..:::|.||
Human  1035 SDMIIDNMTMKFVIIVYGS 1053

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	52/279 (19%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	52/279 (19%)
SLC9C2	XP_011507728.1	Na_H_Exchanger	98..380	CDD:294713
		Ion_trans	638..>731	CDD:278921
		CAP_ED	873..980	CDD:237999	27/166 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900