Protein Alignment Hsc70-4 and ssa1

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_593704.1
• Gene: ssa1 / 2542875
• PomBaseID: SPAC13G7.02c
• Length: 644
• Species: Schizosaccharomyces pombe
• Alignment Length: 652
• Identity: 490/652 - (75%)
• Similarity: 558/652 - (85%)
• Gaps: 9/652 - (1%)

  Fly     1 MSKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQ 65
            |||  ::||||||||||||.|.:.:||||||||||||||||||||||||||||||||||||||..
pombe     1 MSK--SIGIDLGTTYSCVGHFSNNRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPHN 63

  Fly    66 TIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKET 130
            |||||||||||:|:|..||||||||||:|:..||||.|:|.:|.|.|||.|||||||||.||:|:
pombe    64 TIFDAKRLIGRRFNDPEVQSDMKHWPFKVIEKDGKPLIQVEFKGETKTFTPEEISSMVLLKMRES 128

  Fly   131 AEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNV 195
            |||:||..||:||:||||||||||||||||||.|||||||||||||||||||||||:....|.||
pombe   129 AEAFLGGKVTDAVVTVPAYFNDSQRQATKDAGLIAGLNVLRIINEPTAAAIAYGLDRSNQHETNV 193

  Fly   196 LIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRAL 260
            |||||||||||||:|:|::||||||:|||||||||||||:|||.||.||||||:|||:|.|.||:
pombe   194 LIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDSRLVNHFAQEFKRKNKKDITGNARAV 258

  Fly   261 RRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAK 325
            |||||||||||||||||.|||||||||:||.||||||||||||||.|||||:||:||||.|||:|
pombe   259 RRLRTACERAKRTLSSSAQASIEIDSLYEGIDFYTSITRARFEELCADLFRNTMEPVEKVLRDSK 323

  Fly   326 LDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQD 390
            :|||.:::|||||||||||::|:|:.|.|||||..||||||||||||||||||||.||.|::.||
pombe   324 IDKSSVNEIVLVGGSTRIPRIQKLVSDFFNGKEPCKSINPDEAVAYGAAVQAAILVGDTSEKTQD 388

  Fly   391 LLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNL 455
            ||||||.|||||||||||||:.|||||||||||:::.|:||:||||||||||:|||||.|||.||
pombe   389 LLLLDVAPLSLGIETAGGVMTPLIKRNTTIPTKKSEVFSTYADNQPGVLIQVFEGERARTKDCNL 453

  Fly   456 LGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVN 520
            ||||||||||||||||||||||||:||||||||:|||:.|.|..||||||||||||||:|:|||:
pombe   454 LGKFELSGIPPAPRGVPQIEVTFDVDANGILNVSALEKGTGKTQKITITNDKGRLSKEEIDRMVS 518

  Fly   521 EAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQ 585
            |||||:.|||.:...|.|||.||||.::::.:||:.|||.|:..||:..|.....|||:|||.|.
pombe   519 EAEKYKAEDEAETSRIQAKNHLESYAYSLRNSLDDPNLKDKVDASDKEAIDKAVKETIEWLDHNT 583

  Fly   586 LADKEEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGG-PGGMPGAAGAAGAAGAGGAGPTIEE 649
            .|.|:|||.:|||||||.|||:.|:|| ||..|||.||| |||.||     ||.|....||.:||
pombe   584 TAAKDEYEDKQKELEGVANPIMAKIYQ-AGGAPGGAPGGMPGGAPG-----GAPGGADNGPEVEE 642

  Fly   650 VD 651
            ||
pombe   643 VD 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	466/610 (76%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	301/374 (80%)
ssa1	NP_593704.1	PTZ00009	4..644	CDD:240227	485/645 (75%)
		HSPA1-2_6-8-like_NBD	4..378	CDD:212675	300/373 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	824	1.000	Domainoid score	I2
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	964	1.000	Inparanoid score	I43
OMA	1	1.010	-	-		QHG53894
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	1	1.000	-	-		mtm9261
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	1	1.100	-	-	LDO	PTHR19375
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R573
SonicParanoid	1	1.000	-	-		X148
TreeFam	1	0.960	-	-
	13	12.860